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Ardizzone C, Krokos H, Lippe C: Actions of carbaryl on the ionic transport across the isolated skin of Rana esculenta. Comp Biochem Physiol C. 1990;97(1):49-51.
1. Carbaryl, a carbamate used as a pesticide, increases the short-circuit current (SCC) across the isolated frog skin in a dose-dependent manner. 2. This effect is due to the stimulation of sodium absorption and chloride secretion. 3. Carbaryl action on short-circuit current is unrelated to its inhibitory power on cholinesterase; this statement is supported by two experimental results: (a) carbaryl is equally active on both sides of the skin, (b) atropine pretreatment does not inhibit the carbaryl action on SCC. |
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