| Name | apoprotein |
|---|---|
| Synonyms | AD2; APOE; Apo E; Apolipoprotein E; Apolipoprotein E precursor; apoprotein; Apo Es; Apolipoprotein Es… |
| Name | propiconazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7986207 | Ronis MJ, Ingelman-Sundberg M, Badger TM: Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by biosynthesis inhibiting fungicides (EBIFs). Biochem Pharmacol. 1994 Nov 16;48(10):1953-65. In the current study, we examined the effects of two EBIFs in clinical use, and ketoconazole, and two agricultural EBIFs, propiconazole and vinclozolin, on hepatic monooxygenase activities and P450 apoprotein expression in the male Sprague-Dawley rat and the male bobwhite quail. |
6(0,0,1,1) | Details |
| 9972464 | Ronis MJ, Celander M, Badger TM: Cytochrome P450 enzymes in the kidney of the bobwhite quail (Colinus virginianus): induction and inhibition by biosynthesis inhibiting fungicides. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1998 Nov;121(1-3):221-9. Quail kidney microsomes also expressed high levels of a CYP 4A1 cross-reactive apoprotein which was inducible 3-4-fold by ketoconazole. The effects of treatment with the fungicides: propiconazole, vinclozolin, and ketoconazole were examined. |
1(0,0,0,1) | Details |
| 2561184 | Vanden Bossche H, Marichal P, Gorrens J, Coene MC, Willemsens G, Bellens D, Roels I, Moereels H, Janssen PA: Biochemical approaches to selective antifungal activity. Mycoses. 1989;32 Suppl 1:35-52. Azole antifungals (e.g. the imidazoles: miconazole, bifonazole, imazalil, ketoconazole, and the triazoles: diniconazole, triadimenol, propiconazole, fluconazole and itraconazole) inhibit in fungal cells the 14 alpha-demethylation of or 24-methylenedihydrolanosterol. The consequent inhibition of synthesis originates from binding of the unsubstituted (N-3 or N-4) of their or triazole moiety to the heme iron and from binding of their N-1 substituent to the apoprotein of a cytochrome P-450 (P-450 (14) DM) of the endoplasmic reticulum. |
1(0,0,0,1) | Details |