Protein Information

Name gamma aminobutyric acid receptor (protein family or complex)
Synonyms GABA receptor; GABA receptors; GABA(A) receptor; GABA(A) receptors; Gamma aminobutyric acid receptor; Gamma aminobutyric acid receptors

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
18243323 Meyer DA, Carter JM, Johnstone AF, Shafer TJ: Pyrethroid modulation of spontaneous neuronal excitability and neurotransmission in hippocampal neurons in culture. Neurotoxicology. 2008 Mar;29(2):213-25. Epub 2007 Dec 3.


In the presence of inhibitors of GABA receptors, spontaneous excitatory post-synaptic currents (sEPSCs) and spontaneous spike rates were reduced in a concentration-dependent manner by both DM and PM.
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17615118 Narahashi T, Zhao X, Ikeda T, Nagata K, Yeh JZ: Differential actions of insecticides on target sites: basis for selective toxicity. Hum Exp Toxicol. 2007 Apr;26(4):361-6.


Fipronil, a phenylpyrazole, is known to act on the gamma-aminobutyric acid receptor to block the chloride channel.
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