Protein Information

Name Ca v
Synonyms CA V; CA VA; CA5; CA5A; CAV; CAVA; Carbonate dehydratase VA; Carbonic anhydrase V…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
17294162 Clark JM, Symington SB: Pyrethroid action on calcium channels: neurotoxicological implications. Invert Neurosci. 2007 Mar;7(1):3-16. Epub 2007 Feb 9.


These findings delineate a separate action for deltamethrin and implicate N-type rat brain Ca (v) 2.2 voltage-sensitive calcium channels (VSCC) as target sites that are consistent with the in vivo release of neurotransmitter caused by deltamethrin.
4(0,0,0,4) Details
18383452 Clark JM, Symington SB: Neurotoxic implications of the agonistic action of CS-syndrome pyrethroids on the N-type Ca (v) 2.2 calcium channel. Pest Manag Sci. 2008 Jun;64(6):628-38.

4(0,0,0,4) Details
14634047 Hildebrand ME, McRory JE, Snutch TP, Stea A: Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin. J Pharmacol Exp Ther. 2004 Mar;308(3):805-13. Epub 2003 Nov 21.


Allethrin caused blockade with IC (50) values of 7.0 microM for T-type alpha (1G) (Ca (v) 3.1), 6.8 microM for L-type alpha (1C) (Ca (v) 1.2), and 6.7 microM for P/Q-type alpha (1A) (Ca (v) 2.1) channels.
1(0,0,0,1) Details