| Name | muscles |
|---|---|
| Synonyms | COX 7a M; COX VIIa M; COX7A; COX7A1; COX7A1 protein; COX7AH; COX7AM; Cytochrome c oxidase subunit 7a H… |
| Name | aldicarb |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15542610 | Jiang G, Zhuang L, Miyauchi S, Miyake K, Fei YJ, Ganapathy V: A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in -ergic neurons, and involvement in muscle function. J Biol Chem. 2005 Jan 21;280(3):2065-77. Epub 2004 Nov 12. The down-regulation of ceGAT-1 by RNAi leads to an interesting phenotype associated with altered function of body muscles (as evident from changes in thrashing frequency) and enteric muscles (as evident from the rates of defecation failure) and also with altered sensitivity to aldicarb-induced paralysis. |
34(0,1,1,4) | Details |
| 14499607 | Grisoni K, Gieseler K, Mariol MC, Martin E, Carre-Pierrat M, Moulder G, Barstead R, Segalat L: The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin. J Mol Biol. 2003 Oct 3;332(5):1037-46. We report here the molecular and functional characterization of the Caenorhabditis elegans gene stn-1 (F30A10.8), which encodes a syntrophin with homology to vertebrate alpha and beta-syntrophins. stn-1 is expressed in neurons and in muscles of C.elegans. stn-1 mutants resemble dystrophin (dys-1) and dystrobrevin (dyb-1) mutants: they are hyperactive, bend their heads when they move forward, tend to hypercontract, and are hypersensitive to the acetylcholinesterase inhibitor aldicarb. |
33(0,1,1,3) | Details |
| 19545405 | Whittaker AJ, Sternberg PW: Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior. BMC Biol. 2009 Jun 22;7:33. RESULTS: Genetic and laser ablation analysis, in conjunction with behavioral assays were used to determine neurotransmitters, receptors, neurons and muscles required for the regulation of male tail posture. |
2(0,0,0,2) | Details |
| 19066504 | Locke C, Berry K, Kautu B, Lee K, Caldwell K, Caldwell G: Paradigms for pharmacological characterization of C. elegans synaptic transmission mutants. J Vis Exp. 2008 Aug 18;(18). pii: 837. doi: 10.3791/837. In this video, we describe how two complementary neural stimulants, an acetylcholinesterase inhibitor, called aldicarb, and a (GABA) receptor antagonist, called pentylenetetrazole (PTZ), may be employed to specifically characterize signaling at C. elegans neuromuscular junctions (NMJs) and facilitate our understanding of antagonistic neural circuits. Of 302 C. elegans neurons, nineteen GABAergic D-type motor neurons innervate body wall muscles (BWMs), while four GABAergic neurons, called RMEs, innervate head muscles. |
1(0,0,0,1) | Details |
| 7975095 | McEntee K, Poncelet L, Clercx C, Henroteaux M: Acute polymyopathy after poisoning in a dog. Vet Rec. 1994 Jul 23;135(4):88-90. After two days of generalised muscular rigidity, the dog adopted a characteristic fetal position which could be explained by the imbalance between the injuries to the extensor and flexor muscles. |
1(0,0,0,1) | Details |
| 12954868 | Bany IA, Dong MQ, Koelle MR: Genetic and cellular basis for inhibition of Caenorhabditis elegans egg-laying behavior. J Neurosci. 2003 Sep 3;23(22):8060-9. In addition, increasing synaptic by reducing acetylcholinesterase activity, with either mutations or the inhibitor aldicarb, decreased egg laying. Of the nine strongest, six have morphological defects in the ventral-type C (VC) neurons, which synapse onto both the HSNs and the egg-laying muscles and are thus the third cell type comprising the egg-laying system. |
1(0,0,0,1) | Details |
| 11747813 | Garcia LR, Mehta P, Sternberg PW: Regulation of distinct muscle behaviors controls the C. elegans male's copulatory spicules during mating. Cell. 2001 Dec 14;107(6):777-88. Distinct cholinergic neurons use different receptors and channels in the spicule muscles to mediate these contractile behaviors. |
1(0,0,0,1) | Details |
| 9933302 | Bessou C, Giugia JB, Franks CJ, Holden-Dye L, Segalat L: Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission. Neurogenetics. 1998 Dec;2(1):61-72. Based on reporter gene analysis and heterologous promoter expression, the site of action of the dys-1 gene seems to be in muscles. Finally, the dys-1 mutants are hypersensitive to and to the acetylcholinesterase inhibitor aldicarb, suggesting that dys-1 mutations affect cholinergic transmission. |
1(0,0,0,1) | Details |