| Name | protein kinase A (protein family or complex) |
|---|---|
| Synonyms | Protein kinase A; cAMP dependent protein kinase; cAMP dependent protein kinases |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10051215 | Nabekura J, Xu TL, Rhee JS, Li JS, Akaike N: Alpha2-adrenoceptor-mediated enhancement of response in rat sacral dorsal commissural neurons. Neuroscience. 1999 Mar;89(1):29-41. In addition, potentiated the strychnine-sensitive postsynaptic currents evoked in a slice preparation of sacral dorsal commissural nucleus. N-[2 (methylamino) ethyl]-5-isoquinoline sulfonamide dihydrochloride, protein kinase A inhibitor, mimicked the effect of on response. |
2(0,0,0,2) | Details |
| 9518725 | Han Y, Slaughter MM: Protein kinases modulate two currents in salamander retinal ganglion cells. J Physiol. 1998 May 1;508 ( Pt 3):681-90. Nanomolar concentrations of strychnine selectively blocked the fast phase of the current and reversed the effect of OAG, but not that of forskolin. H-89, a protein kinase A (PKA) inhibitor, blocked the effect of forskolin. 4. |
2(0,0,0,2) | Details |
| 11740501 | Ahmadi S, Lippross S, Neuhuber WL, Zeilhofer HU: PGE (2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons. Nat Neurosci. 2002 Jan;5(1):34-40. We identified the inhibitory (strychnine-sensitive) glycine receptor as a specific target of PGE (2). Inhibition of glycine receptors occurred via a postsynaptic mechanism involving the activation of EP2 receptors, cholera-toxin-sensitive G-proteins and cAMP-dependent protein kinase. |
1(0,0,0,1) | Details |
| 17196941 | Yan L, Suneja SK, Potashner SJ: Protein kinases regulate glycine receptor binding in brain stem auditory nuclei after unilateral cochlear ablation. Brain Res. 2007 Mar 2;1135(1):102-6. Epub 2007 Jan 2. We found previously that unilateral cochlear ablation (UCA) in young adult guinea pigs decreased [3H] strychnine binding activity in several brain stem auditory nuclei. This study determined if the UCA-induced deficit could be regulated by protein kinase C (PKC), protein kinase A (PKA) or Ca2+/calmodulin-dependent protein kinase II (CaMKII). |
1(0,0,0,1) | Details |
| 8987801 | Bonci A, Williams JT: Increased probability of release during withdrawal from morphine. . J Neurosci. 1997 Jan 15;17(2):796-803. In addition, activation of adenylyl cyclase, with forskolin, and cAMP-dependent protein kinase, with Sp-cAMPS, caused a larger increase in IPSCs in slices from morphine-treated animals. |
1(0,0,0,1) | Details |
| 18440992 | Hou M, Duan L, Slaughter MM: Synaptic inhibition by acting at a metabotropic receptor in tiger salamander retina. J Physiol. 2008 Jun 15;586(Pt 12):2913-26. Epub 2008 Apr 25. In retina, we found a strychnine-insensitive response in bipolar and ganglion cells. It was G-protein mediated and protein kinase A dependent. |
1(0,0,0,1) | Details |
| 15356198 | Carpenter-Hyland EP, Woodward JJ, Chandler LJ: Chronic induces synaptic but not extrasynaptic targeting of NMDA receptors. J Neurosci. 2004 Sep 8;24(36):7859-68. The increase in synaptic NMDA receptor clustering was prevented by addition of a protein kinase A inhibitor or by coexposure to a low concentration of and was reversed when was removed from the cultures. |
1(0,0,0,1) | Details |
| 14660708 | Saywell SA, Feldman JL: Dynamic interactions of excitatory and inhibitory inputs in hypoglossal motoneurones: respiratory phasing and modulation by PKA. J Physiol. 2004 Feb 1;554(Pt 3):879-89. Epub 2003 Dec 5. In non-inhibited motoneurones, neither bicuculline nor strychnine markedly changed inspiratory drive currents. Inhibitory currents in XII motoneurones were potentiated by protein kinase A (PKA) activity. |
1(0,0,0,1) | Details |
| 8899617 | Nabekura J, Omura T, Akaike N: Alpha 2 adrenoceptor potentiates glycine receptor-mediated response through protein kinase A in rat substantia nigra neurons. J Neurophysiol. 1996 Oct;76(4):2447-54. Both currents were antagonized by 10 (-6) M strychnine, thus indicating that acts on strychnine-sensitive glycine receptor on the SN neurons. 3. |
1(0,0,0,1) | Details |
| 11283224 | Akopian A, Witkovsky P: Intracellular reduces light-induced excitatory post-synaptic responses in salamander retinal ganglion cells. J Physiol. 2001 Apr 1;532(Pt 1):43-53. In the presence of strychnine and picrotoxin, ganglion cells responded to light onset and offset with transient inward currents at -70 mV. |
0(0,0,0,0) | Details |
| 11784734 | Svensson E, Grillner S, Parker D: Synaptically evoked membrane potential oscillations induced by substance P in lamprey motor neurons. J Neurophysiol. 2002 Jan;87(1):113-21. Blocking glycinergic inputs with strychnine resulted in large depolarizing plateaus and bursts of spikes. |
0(0,0,0,0) | Details |