Protein Information

Name C18
Synonyms B1; D1; BBS 9; BBS9; BBS9 GENE; Bardet Biedl syndrome 9 protein; C18; PTH responsive osteosarcoma B1 protein…

Compound Information

Name streptomycin
CAS

Reference List

PubMed Abstract RScore(About this table)
17441221 Cherlet M, De Baere S, De Backer P: Quantitative determination of dihydrostreptomycin in bovine tissues and milk by liquid chromatography-electrospray ionization-tandem mass spectrometry. J Mass Spectrom. 2007 May;42(5):647-56.

Ion-pair chromatography, using a mixture of 20 mM pentafluoropropionic acid in water and acetonitrile as the mobile phase, was used to retain DHS and the internal standard streptomycin (STR) on a Nucleosil (5 microm) reversed-phase C18 column.
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16806244 Sarri AK, Megoulas NC, Koupparis MA: Development of a novel method based on liquid chromatography-evaporative light scattering detection for the direct determination of streptomycin and dihydrostreptomycin in raw materials, pharmaceutical formulations, culture media and plasma. J Chromatogr A. 2006 Jul 28;1122(1-2):275-8. Epub 2006 Jun 23.

Utilizing a ThermoHypersil BetaBasic C18 analytical column, evaporation temperature of 50 degrees C and pressure of nebulizing gas (nitrogen) of 3.5 bar, the optimized mobile phase was 1.25 mL L (-1) TFA aqueous solution, in an isocratic mode at a rate of 1.0 mL min (-1).
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19286013 Granja RH, Nino AM, Zucchetti RA, Nino RE, Patel R, Salerno AG: Determination of streptomycin residues in honey by liquid chromatography-tandem mass spectrometry. Anal Chim Acta. 2009 Apr 1;637(1-2):64-7. Epub 2009 Jan 10.

The chromatography separation was performed on a Gemini 5 microm C18 (50 mm x 2 mm) column using 5mM heptafluorbutiric acid/acetonitrile (85:15) as the mobile phase at a flow rate of 0.2 mLmin (-1).
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15084085 Pang GF, Zhang JJ, Cao YZ, Fan CL, Lin XM, Li ZY, Jia GQ: Evaluation of analyte stability and method ruggedness in the determination of streptomycin residues in honey by liquid chromatography with post-column derivatization. J AOAC Int. 2004 Jan-Feb;87(1):39-44.

The continuous 4-year quality analysis also found that C18 solid-phase extraction cartridges should be standardized to ensure that the analytical results are accurate when different lots of cartridges are used.
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