Protein Information

Name ant 3
Synonyms ADP/ATP translocase 3; Adenine nucleotide translocator 2; ADP/ATP translocator of liver; ANT 3; ANT3; ANT3Y; Adenine nucleotide translocator 3; CDABP0051…

Compound Information

Name streptomycin
CAS

Reference List

PubMed Abstract RScore(About this table)
18424533 Gow SP, Waldner CL, Harel J, Boerlin P: Associations between antimicrobial resistance genes in fecal generic Escherichia coli isolates from cow-calf herds in western Canada. Appl Environ Microbiol. 2008 Jun;74(12):3658-66. Epub 2008 Apr 18.

The strongest associations observed were those between genes for resistance to chloramphenicol (catI) and trimethoprim (dhfrI) (odds ratio [OR] = 214; P = 0.0001), sulfonamide (sul1) and chloramphenicol (catI) (OR = 96.9; P = 0.0001), streptomycin [ant (3'')-Ia (aadA1)] and trimethoprim (dhfrI) (OR = 96.2; P = 0.0001), sulfonamide (sul1) and streptomycin [ant (3'')-Ia (aadA1)] (OR = 79.3; P = 0.0001), and tetracycline [tet (B)] and sulfonamides (sul2) (OR = 25.7; P = 0.0001).
8(0,0,1,3) Details
17701242 Srinivasan V, Nam HM, Sawant AA, Headrick SI, Nguyen LT, Oliver SP: Distribution of tetracycline and streptomycin resistance genes and class 1 integrons in Enterobacteriaceae isolated from dairy and nondairy farm soils. Microb Ecol. 2008 Feb;55(2):184-93. Epub 2007 Aug 15.

Similarly, a higher prevalence of streptomycin resistance genes including strA (12.5%), strB (12.5%), ant (3'') (12.5), aph (6)-1c (12.5%), aph (3'') (10.8%), and addA (5.4%) was detected in bacteria isolated from dairy farm soils than in nondairy soils.
6(0,0,1,1) Details
19361944 Cho YJ, Moon DC, Jin JS, Choi CH, Lee YC, Lee JC: Genetic basis of resistance to aminoglycosides in Acinetobacter spp. and spread of armA in Acinetobacter baumannii sequence group 1 in Korean hospitals. Diagn Microbiol Infect Dis. 2009 Jun;64(2):185-90. Epub 2009 Apr 9.

The MIC (50) and MIC (90) of Acinetobacter baumannii isolates (n = 61) to amikacin, gentamicin, isepamycin spectinomycin, streptomycin, and tobramycin were higher than those of Acinetobacter genomic species 13TU isolates (n = 14).
Genes encoding aminoglycoside-modifying enzymes, ant (3")-Ia, aac (6')-Ib, aph (3')-1a, aac (3)-Ia, and aph (3')-VI, and 16S ribosomal RNA (rRNA) methylase armA were detected. ant (3")-Ia and aac (6')-Ib were commonly detected in both Acinetobacter spp., but armA and aph (3")-Ia were only detected in A. baumannii. armA was located on the plasmids.
1(0,0,0,1) Details
17030911 Chen YG, Qu TT, Yu YS, Zhou JY, Li LJ: Insertion sequence ISEcp1-like element connected with a novel aph (2'') allele [aph (2'')-Ie] conferring high-level gentamicin resistance and a novel streptomycin adenylyltransferase gene in Enterococcus. J Med Microbiol. 2006 Nov;55(Pt 11):1521-5.

0(0,0,0,0) Details