| Name | interleukin 18 |
|---|---|
| Synonyms | IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL 1g; IL18; IL1F4; Iboctadekin… |
| Name | streptomycin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19237529 | Winter SE, Thiennimitr P, Nuccio SP, Haneda T, Winter MG, Wilson RP, Russell JM, Henry T, Tran QT, Lawhon SD, Gomez G, Bevins CL, Russmann H, Monack DM, Adams LG, Baumler AJ: Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection. Infect Immun. 2009 May;77(5):1904-16. Epub 2009 Feb 23. In vitro, caspase-1 can be activated by cytosolic delivery of flagellin, resulting in release of the interferon gamma inducing factor interleukin-18 (IL-18). Experiments with streptomycin-pretreated caspase-1-deficient mice suggested that induction of gamma interferon expression in the murine cecum early (12 h) after serotype Typhimurium infection was caspase-1 dependent but independent of flagellin pattern recognition. |
1(0,0,0,1) | Details |
| 16717117 | Lara-Tejero M, Sutterwala FS, Ogura Y, Grant EP, Bertin J, Coyle AJ, Flavell RA, Galan JE: Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med. 2006 Jun 12;203(6):1407-12. Epub 2006 May 22. Caspase-1 is required for the secretion of proinflammatory cytokines, such as interleukin (IL)-1beta and IL-18, and is involved in the control of many bacterial infections. |
1(0,0,0,1) | Details |
| 16177391 | Fukasawa Y, Kawamura I, Uchiyama R, Yamamoto K, Kaku T, Tominaga T, Nomura T, Ichiyama S, Ezaki T, Mitsuyama M: Streptomycin-dependent exhibition of cytokine-inducing activity in streptomycin-dependent Mycobacterium tuberculosis strain 18b. Infect Immun. 2005 Oct;73(10):7051-5. Gamma interferon production by natural killer cells depending on interleukin-12 and interleukin-18 was induced only in the presence of a high dose of streptomycin. |
31(0,1,1,1) | Details |