| Name | dopamine beta hydroxylase |
|---|---|
| Synonyms | DBH; DBM; Dopamine beta hydroxylase; Dopamine beta monooxygenase; Dopamine beta hydroxylase precursor; dopamine beta hydroxylase (dopamine beta monooxygenase); DBH; Dopamine beta hydroxylases… |
| Name | maneb |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6420938 | Serio R, Long RA, Taylor JE, Tolman RL, Weppelman RM, Olson G: The antifertility and antiadrenergic actions of thiocarbamate fungicides in laying hens. Toxicol Appl Pharmacol. 1984 Feb;72(2):333-42. The effects of the thiocarbamate fungicides, thiram, ziram, ferbam, maneb, and zineb, on synthesis by laying hens were investigated. Inhibition experiments with dopamine beta-hydroxylase purified from chicken adrenals indicated that thiram, ziram, and ferbam are potent competitive inhibitors with the substrate the substrate |
2(0,0,0,2) | Details |
| 3006637 | Komulainen H, Savolainen K: Effect of dithiocarbamate fungicides and thiurams on 3H-haloperidol binding in rat brain. Arch Toxicol Suppl. 1985;8:77-9. As one biochemical indicator of the toxicity, dopamine-beta-hydroxylase is inhibited in the brain. It appeared that ferbam, maneb, nabam, zineb, disulfiram, thiram and ethylene thiourea did not change significantly D2-receptor binding at doses which were already overtly toxic. |
1(0,0,0,1) | Details |
| 3938269 | Laisi A, Tuominen R, Mannisto P, Savolainen K, Mattila J: The effect of maneb, zineb, and ethylenethiourea on the humoral activity of the pituitary-thyroid axis in rat. Arch Toxicol Suppl. 1985;8:253-8. The mechanism behind this action may be the inhibition of dopamine-beta-hydroxylase. |
1(0,0,0,1) | Details |