maneb
Identification (Source:EPA,EU)
ID |
600 |
Name |
maneb |
CAS |
12427-38-2 |
IUPAC |
manganese ethylenebis(dithiocarbamate) (polymeric) |
Inchi |
|
CIPAC |
61 |
EPA Code |
014505 |
Formula |
C4H6MnN2S4 |
SMILES |
[Mn+2].[S-]C(=S)NCCNC(=S)[S-] |
Status |
Approved |
Classification
Properties (Source:PubChem)
Molecular Weight |
265.30 |
Physical State |
Yellow powder |
AlogP |
2.951 |
H-Bond Donor |
2 |
H-Bond Acceptor |
4 |
Surface Area |
192.28 |
Polar Surface Area |
145.83 |
Structure
Ecotoxicology (Source:PPDB,IPM)
Species |
Method |
Study Time |
Dose Type |
Value |
Algae |
Acute |
72 hour |
EC50, growth |
0.011 mg l-1 |
Aquatic crustaceans |
Acute |
96 hour |
LC50 |
2.4 mg l-1 |
Aquatic invertebrates |
Acute |
48 hour |
EC50 |
0.31 mg l-1 |
Aquatic invertebrates |
Chronic |
21 day |
NOEC |
0.0023 mg l-1 |
Birds |
Acute |
|
LD50 |
> 1467 mg kg-1 |
Birds |
Short term dietary |
|
LC50/LD50 |
> 5000 mg/kg feed |
Earthworms |
Chronic |
14 day |
NOEC, reproduction |
8.0 mg kg-1 |
Earthworms |
Acute |
14 day |
LD50 |
840 mg kg-1 |
Fish |
Acute |
96 hour |
LC50 |
0.23 mg l-1 |
Fish |
Chronic |
21 day |
NOEC |
0.0065 mg l-1 |
Honeybees |
Acute |
48 hour |
LD50 |
> 89.5 μg bee-1 |
Mammals |
Acute oral |
|
LD50 |
> 5000 mg kg-1 |
|
Bio-concentration factor |
|
CT50 |
Not available days |
Related targets
Target Name |
RScore (About this table) |
|
alpha synuclein
|
161(1,3,5,11) |
Details |
Bcl xL
|
82(1,1,1,2) |
Details |
carbonic dehydratase
|
47(0,1,3,7) |
Details |
CYP2E1
|
40(0,1,2,5) |
Details |
GSTA4 4
|
39(0,1,2,4) |
Details |
tyrosine hydroxylase
|
37(0,1,1,7) |
Details |
C18
|
32(0,1,1,2) |
Details |
superoxide dismutase
|
15(0,0,2,5) |
Details |
Acetylcholinesterase
|
15(0,0,1,10) |
Details |
bcl 2
|
13(0,0,2,3) |
Details |
lactate dehydrogenase (protein family or complex)
|
9(0,0,1,4) |
Details |
dynamin (protein family or complex)
|
8(0,0,0,8) |
Details |
CS2
|
7(0,0,1,2) |
Details |
cytochrome P450 (protein family or complex)
|
7(0,0,1,2) |
Details |
SVAS
|
7(0,0,1,2) |
Details |
M83
|
7(0,0,1,2) |
Details |
Basalin
|
6(0,0,1,1) |
Details |
glutathione S transferase
|
6(0,0,0,6) |
Details |
MB 1
|
6(0,0,1,1) |
Details |
OV 1
|
6(0,0,1,1) |
Details |
cholinesterase
|
5(0,0,0,5) |
Details |
FLR1
|
5(0,0,0,5) |
Details |
CS 2
|
4(0,0,0,4) |
Details |
P30
|
4(0,0,0,4) |
Details |
catalase
|
4(0,0,0,4) |
Details |
dopamine beta hydroxylase
|
4(0,0,0,4) |
Details |
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