maneb

Identification (Source:EPA,EU)

ID 600
Name maneb
CAS 12427-38-2
IUPAC manganese ethylenebis(dithiocarbamate) (polymeric)
Inchi
CIPAC 61
EPA Code 014505
Formula C4H6MnN2S4
SMILES [Mn+2].[S-]C(=S)NCCNC(=S)[S-]
Status Approved

Classification

Mode of Action Non-specific with protective action
Pesticide Type Fungicide
Chemical Group Dithiocarbamate
Classification polymeric dithiocarbamate fungicides

Properties (Source:PubChem)

Molecular Weight 265.30
Physical State Yellow powder
AlogP 2.951
H-Bond Donor 2
H-Bond Acceptor 4
Surface Area 192.28
Polar Surface Area 145.83

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 0.011 mg l-1
Aquatic crustaceans Acute 96 hour LC50 2.4 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.31 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.0023 mg l-1
Birds Acute LD50 > 1467 mg kg-1
Birds Short term dietary LC50/LD50 > 5000 mg/kg feed
Earthworms Chronic 14 day NOEC, reproduction 8.0 mg kg-1
Earthworms Acute 14 day LD50 840 mg kg-1
Fish Acute 96 hour LC50 0.23 mg l-1
Fish Chronic 21 day NOEC 0.0065 mg l-1
Honeybees Acute 48 hour LD50 > 89.5 μg bee-1
Mammals Acute oral LD50 > 5000 mg kg-1
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
alpha synuclein 161(1,3,5,11) Details
Bcl xL 82(1,1,1,2) Details
carbonic dehydratase 47(0,1,3,7) Details
CYP2E1 40(0,1,2,5) Details
GSTA4 4 39(0,1,2,4) Details
tyrosine hydroxylase 37(0,1,1,7) Details
C18 32(0,1,1,2) Details
superoxide dismutase 15(0,0,2,5) Details
Acetylcholinesterase 15(0,0,1,10) Details
bcl 2 13(0,0,2,3) Details
lactate dehydrogenase (protein family or complex) 9(0,0,1,4) Details
dynamin (protein family or complex) 8(0,0,0,8) Details
CS2 7(0,0,1,2) Details
cytochrome P450 (protein family or complex) 7(0,0,1,2) Details
SVAS 7(0,0,1,2) Details
M83 7(0,0,1,2) Details
Basalin 6(0,0,1,1) Details
glutathione S transferase 6(0,0,0,6) Details
MB 1 6(0,0,1,1) Details
OV 1 6(0,0,1,1) Details
cholinesterase 5(0,0,0,5) Details
FLR1 5(0,0,0,5) Details
CS 2 4(0,0,0,4) Details
P30 4(0,0,0,4) Details
catalase 4(0,0,0,4) Details
dopamine beta hydroxylase 4(0,0,0,4) Details
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