| Name | aryl hydrocarbon hydroxylase |
|---|---|
| Synonyms | Aryl hydrocarbon hydroxylase; Flavoprotein linked monooxygenase; Xenobiotic monooxygenase; Microsomal monooxygenase; CP37; CYP3A7; CYPIIIA 7; CYPIIIA7… |
| Name | malathion |
|---|---|
| CAS | diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17110060 | Buratti FM, Leoni C, Testai E: Foetal and adult human CYP3A isoforms in the bioactivation of organophosphorothionate insecticides. Toxicol Lett. 2006 Dec 15;167(3):245-55. Epub 2006 Oct 24. Since OPT-induced neurodevelopmental effects may be due to in situ bioactivation by foetal enzymes, the catalytic activity of the foetal CYP3A7 toward chlorpyrifos (CPF), parathion (PAR), malathion (MAL) and fenthion (FEN) has been assessed by using recombinant enzymes. |
7(0,0,1,2) | Details |
| 3488742 | Koizumi A, Hasegawa L, Thomas IK, Imamura T: Effect of induction of T-cell-dependent antibody with sheep red blood cells on P-450-dependent and -independent xenobiotic metabolizing enzymes. Biochem Pharmacol. 1986 Aug 15;35(16):2743-8. The basal levels of aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin O-deethylase (7-Ec) were different among congenic strains. Similarly, the difference due to the strain and the H-2 locus was detected in the activities of P-450-independent enzymes such as malathion and diethyl carboxylesterases, glutathione S-transferase, and epoxide hydrolases in microsomal and cytosolic fractions. |
1(0,0,0,1) | Details |