Protein Information

Name polymerases
Synonyms ERVK 2; ERVK2; HERV K; Polymerase; Polymerases

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
2087919 Walter Z, Wiszkowska H: Effect of malathion on the initiation and elongation steps of transcription. Acta Biochim Pol. 1990;37(1):73-6.

In isolated cell nuclei of pig thymus malathion, S-1,2-bis (ethoxycarbonyl)-ethyl-O,O-dimethyldithiophosphate inhibited both initiation and elongation of all three classes of nuclear RNA polymerases; proflavin was used as an inhibitor of initiation, and actinomycin, as an inhibitor of elongation.
81(1,1,1,1) Details