| 11691539 |
Tahara S, Fukuda K, Kodama H, Kato T, Miyoshi S, Ogawa S: Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes. J Am Coll Cardiol. 2001 Nov 1;38(5):1554-63.
METHODS: Primary cultured rat cardiomyocytes were stimulated with four different KBs-4-aminopyridine (4-AP), E-4031, tetra-ethylammonium and quinidine-and phosphorylation of ERK, proline-rich tyrosine kinase 2 (Pyk2) and epidermal growth factor receptor (EGFR) was detected. |
164(2,2,2,4) |
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| 12599214 |
Camina JP, Diaz-Rodriguez E, Harks EG, Theuvenet AP, Ypey DL, Casanueva FF: Lipid factor (bVLF) from bovine vitreous body evokes in EGFR-T17 cells a Ca2+-dependent K+ current associated with inositol 1,4,5-trisphosphate-independent Ca2+ mobilization. J Cell Physiol. 2003 Apr;195(1):108-18.
The bVLF-induced hyperpolarization was blocked by the K (+) channel blockers, quinine and tetraethylamonium chloride, and partially affected by 4-aminopyridine. |
2(0,0,0,2) |
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