| Name | adenylyl cyclase |
|---|---|
| Synonyms | ADCY 7; ATP pyrophosphate lyase; Adenylyl cyclase; ADCY7; ADCY7 protein; ATP pyrophosphate lyase 7; Adenylate cyclase 7; Adenylate cyclase type 7… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8887958 | Hardiman O, Sweeney DJ, Keenan AK: Adenylyl cyclase activity in clonally derived human myoblast cultures: evidence for myoblast heterogeneity. Neuromuscul Disord. 1996 Aug;6(4):283-91. In control cultures, there was considerable inter-clonal variation in basal, sodium-fluoride and forskolin-stimulated adenylyl cyclase activity. |
11(0,0,1,6) | Details |
| 15306227 | Hashim S, Li Y, Nagakura A, Takeo S, Anand-Srivastava MB: Modulation of G-protein expression and adenylyl cyclase signaling by high in vascular smooth muscle. Cardiovasc Res. 2004 Sep 1;63(4):709-18. On the other hand, the stimulatory effects of GTPgammaS, glucagon, isoproterenol, FSK and sodium fluoride on adenylyl cyclase were significantly augmented in hyperglycemic cells as compared to control cells, whereas basal adenylyl cyclase activity was significantly lower in hyperglycemic cells as compared to control cells. |
11(0,0,1,6) | Details |
| 10608476 | Ge C, Garcia R, Anand-Srivastava MB: Altered expression of Gi-protein and adenylyl cyclase activity in hearts from one kidney one clip hypertensive rats: effect of captopril. J Hypertens. 1999 Nov;17(11):1617-26. 5'-[3'-thio] (GTPgammaS), isoproterenol, glucagon, sodium fluoride (NaF) and forskolin (FSK) stimulated adenylyl cyclase activity in hearts from control and hypertensive rats to varying degrees; however, the stimulations were significantly less in hypertensive rats compared with control rats. |
10(0,0,1,5) | Details |
| 9169417 | Abell AN, Segaloff DL: Evidence for the direct involvement of transmembrane region 6 of the lutropin/choriogonadotropin receptor in activating Gs. J Biol Chem. 1997 Jun 6;272(23):14586-91. This study demonstrates that a peptide corresponding to the lower portion of the sixth transmembrane region of the LHR can significantly activate adenylyl cyclase activity. |
1(0,0,0,1) | Details |
| 15196683 | Borasio PG, Cervellati F, Pavan B, Pareschi MC: "Low" concentrations of sodium fluoride inhibit neurotransmitter release from the guinea-pig superior cervical ganglion. Neurosci Lett. 2004 Jul 1;364(2):86-9. The electrically evoked (1 Hz, 5 min) [3H] release was inhibited by "low" F- concentrations (1-2.5 mM), by the adenylyl cyclase blocker MDL 12330A (10 microM), alone and in combination with 1 mM NaF, and increased by 0.5 mM 8Br-cAMP, 100 microM forskolin and 0.5 mM 3-isobutyl-1-methylxantine. |
1(0,0,0,1) | Details |
| 15877111 | Amira S, Mule F: Effects of sodium fluoride on the mechanical activity in mouse gastric preparations. Can J Physiol Pharmacol. 2005 Apr;83(4):367-73. Moreover, it was abolished by neomycin (an inhibitor of phospholipase C) and potentiated by SQ22536 (an inhibitor of adenylyl cyclase). |
1(0,0,0,1) | Details |
| 14754571 | Meyer A, Seidler FJ, Slotkin TA: Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling. Environ Health Perspect. 2004 Feb;112(2):170-8. In the present study, we evaluated the immediate and long-term effects of CPF exposure of rats during different developmental windows [gestational days (GD) 9-12 or 17-20, postnatal days (PN) 1-4 or 11-14] on the adenylyl cyclase (AC) signaling cascade in the heart and liver. In addition to basal AC activity, we assessed the responses to direct AC stimulants (forskolin, Mn2+); to isoproterenol and glucagon, which activate signaling through specific membrane receptors; and to sodium fluoride, which activates the G-proteins that couple the receptors to AC. |
1(0,0,0,1) | Details |
| 11032978 | Emamghoreishi M, Li PP, Schlichter L, Parikh SV, Cooke R, Warsh JJ: Associated disturbances in homeostasis and G protein-mediated cAMP signaling in bipolar I disorder. Biol Psychiatry. 2000 Oct 1;48(7):665-73. METHODS: To test this hypothesis, the beta-adrenergic agonist, isoproterenol, and the G protein activator, sodium fluoride (NaF), were used to stimulate cAMP production in B lymphoblasts from healthy and BP-I subjects phenotyped on basal intracellular concentration ([Ca (2+)](B)). cAMP was measured by radioimmunoassay and [Ca (2+)](B) by ratiometric fluorometry with fura-2. This suggests the differences in NaF response resulted from higher basal adenylyl cyclase activity. |
1(0,0,0,1) | Details |
| 15106810 | Hashim S, Anand-Srivastava MB: Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins. J Hypertens. 2004 Jan;22(1):181-90. In addition, the stimulatory effects of 5'-gamma-thiotriphosphate (GTPgammaS), isoproterenol, 5'-N-ethylcarboxamideadenosine (NECA), glucagon, forskolin (FSK) and sodium fluoride (NaF) on adenylyl cyclase, which were diminished in L-NAME-treated rats, were reversed by losartan treatment. |
9(0,0,1,4) | Details |
| 11900377 | Anand-Srivastava MB, Wang R, Liu YY: Alterations in g-protein-linked signal transduction in vascular smooth muscle in diabetes. Adv Exp Med Biol. 2001;498:263-71. On the other hand, the stimulatory effects of GTPgammaS, isoproterenol, glucagon, forskolin (FSK) and sodium fluoride on adenylyl cyclase were enhanced in STZ-rats. |
9(0,0,1,4) | Details |
| 11705775 | Auman JT, Seidler FJ, Tate CA, Slotkin TA: Beta-adrenoceptor-mediated cell signaling in the neonatal heart and liver: responses to terbutaline. Am J Physiol Regul Integr Comp Physiol. 2001 Dec;281(6):R1895-901. Despite the reduction in cardiac beta-ARs, receptor desensitization was absent as evidenced by the maintained ability of isoproterenol to stimulate adenylyl cyclase (AC) in membrane preparations. |
1(0,0,0,1) | Details |
| 8621516 | Toyoshige M, Basi NS, Rebois RV: effects on Gs subunit dissociation. J Biol Chem. 1996 Apr 12;271(15):8791-5. The stimulatory nucleotide binding protein (Gs) is heterotrimeric ( alpha beta gamma), and mediates activation of adenylyl cyclase by a ligand-receptor complex. |
1(0,0,0,1) | Details |
| 16269967 | Lappas G, Daou GB, Anand-Srivastava MB: Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats. J Hypertens. 2005 Dec;23(12):2251-61. Similarly, diminished stimulation of adenylyl cyclase by GTPgammaS, isoproterenol and sodium fluoride in SHR was also restored towards control WKY rat levels by NAC and DPI treatments. |
9(0,0,1,4) | Details |
| 11562400 | Kim SW, Cho SH, Oh BS, Yeum CH, Choi KC, Ahn KY, Lee J: Diminished renal expression of aquaporin water channels in rats with experimental bilateral ureteral obstruction. J Am Soc Nephrol. 2001 Oct;12(10):2019-28. The protein expression of G (salpha) was decreased in the cortex, outer medulla, and inner medulla, whereas that of adenylyl cyclase VI was decreased in the outer and inner medullae. cAMP generation stimulated by arginine vasopressin was decreased in the cortex, outer medulla, and inner medulla. cAMP generation in response to forskolin was decreased in the outer and inner medullae, whereas that in response to sodium fluoride was decreased in the cortex, outer medulla, and inner medulla. |
8(0,0,1,3) | Details |
| 9502768 | Xiao RP, Tomhave ED, Wang DJ, Ji X, Boluyt MO, Cheng H, Lakatta EG, Koch WJ: Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases. J Clin Invest. 1998 Mar 15;101(6):1273-82. This was associated with a nonselective reduction in the density of both beta-AR subtypes and a reduction in membrane adenylyl cyclase response to both beta-AR subtype agonists, NaF or forskolin. |
1(0,0,0,1) | Details |
| 11388643 | Lee J, Yoo KS, Kang DG, Kim SW, Choi KC: Gentamicin decreases the abundance of aquaporin water channels in rat kidney. Jpn J Pharmacol. 2001 Apr;85(4):391-8. The protein expression of AQP1-3 channels and the catalytic activity of adenylyl cyclase were determined in the kidney. The cAMP generation in response to arginine vasopressin or sodium fluoride was decreased by gentamicin, while that to forskolin was not significantly altered. |
1(0,0,0,1) | Details |
| 19133318 | Wann BP, D'Anjou B, Bah TM, Webster HH, Godbout R, Rousseau G: Effect of olfactory bulbectomy on adenylyl cyclase activity in the limbic system. Brain Res Bull. 2009 Apr 6;79(1):32-6. Epub 2009 Jan 6. Here, we used the olfactory bulbectomy (OBX) model of depression to characterize cAMP-second messenger signaling pathways, i.e., adenylyl cyclase activity (basal, sodium fluoride (NaF)- and forskolin-stimulated conditions) as well as Gi and Gs protein levels in different regions of the limbic system. |
8(0,0,1,3) | Details |
| 8890832 | Anzai T, Yoshikawa T, Baba A, Nishimura H, Shiraki H, Nagami K, Suzuki M, Wainai Y, Ogawa S: Myocardial sympathetic denervation prevents chamber-specific alteration of beta-adrenergic transmembrane signaling in rabbits with heart failure. J Am Coll Cardiol. 1996 Nov 1;28(5):1314-22. The beta-adrenoceptor densities and isoproterenol plus 5'-guanylylimidodiphosphate-, 5'-guanylylimidodiphosphate- and sodium fluoride-stimulated adenylyl cyclase activities were decreased only in the failing left ventricle of the vehicle-pretreated aortic regurgitation group, but in both ventricles of the -pretreated aortic regurgitation group. |
8(0,0,1,3) | Details |
| 10677348 | Palaparti A, Li Y, Anand-Srivastava MB: Inhibition of atrial natriuretic peptide (ANP) C receptor expression by antisense oligodeoxynucleotides in A10 vascular smooth-muscle cells is associated with attenuation of ANP-C-receptor-mediated inhibition of adenylyl cyclase. Biochem J. 2000 Mar 1;346 Pt 2:313-20. In addition, the stimulatory effects of nucleotides, isoproterenol, sodium fluoride and forskolin as well as the inhibitory effects of angiotensin II on adenylyl cyclase were not affected by antisense-oligonucleotide treatment. |
7(0,0,0,7) | Details |
| 12208125 | Yeum CH, Kim SW, Kim NH, Choi KC, Lee J: Increased expression of aquaporin water channels in hypothyroid rat kidney. Pharmacol Res. 2002 Jul;46(1):85-8. The adenylyl cyclase activity provoked by arginine vasopressin (AVP), sodium fluoride, or forskolin was blunted in the hypothyroid kidney, while plasma levels of AVP were not significantly changed. |
0(0,0,0,0) | Details |
| 9070961 | Uekita K, Tobise K, Onodera S: Enhancement of the cardiac beta-adrenergic system at an early diabetic state in spontaneously diabetic Chinese hamsters. Jpn Circ J. 1997 Jan;61(1):64-73. These changes preceded both the development of cardiac hypertrophy and the enhanced response of adenylyl cyclase to isoproterenol plus 5'-guanylylimidodiphosphate [Gpp (NH) p], sodium fluoride, or forskolin stimulation. |
7(0,0,1,2) | Details |
| 19955819 | Ma SK, Bae EH, Kim IJ, Choi C, Lee J, Kim SW: Altered renal expression of aquaporin water channels and transporters in rats with two-kidney, one-clip hypertension. Kidney Blood Press Res. 2009;32(6):411-20. Epub 2009 Dec 3. The adenylyl cyclase activity provoked by arginine vasopressin, sodium fluoride or forskolin was blunted in the clipped kidney, but remained unaltered in the contralateral kidney. |
7(0,0,1,2) | Details |
| 10100877 | Persad S, Dhalla NS: Modification of beta-adrenoceptors and adenylyl cyclase in hearts perfused with hypochlorous acid. Can J Physiol Pharmacol. 1998 Oct-Nov;76(10-11):961-6. |
6(0,0,0,6) | Details |
| 9780316 | Lindeman KS, Hirshman CA, Kuhl JS, Levitsky HI, Emala CW: Chronic pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells. Biol Reprod. 1998 Nov;59(5):1108-15. |
6(0,0,0,6) | Details |
| 10072719 | Persad S, Elimban V, Siddiqui F, Dhalla NS: Alterations in cardiac membrane beta-adrenoceptors and adenylyl cyclase due to hypochlorous acid. J Mol Cell Cardiol. 1999 Jan;31(1):101-11. |
5(0,0,0,5) | Details |
| 9486243 | Persad S, Rupp H, Jindal R, Arneja J, Dhalla NS: Modification of cardiac beta-adrenoceptor mechanisms by H2O2. Am J Physiol. 1998 Feb;274(2 Pt 2):H416-23. From the role of oxidative stress in cardiac dysfunction, we investigated the effect of H2O2, an activated species of on beta-adrenoceptors, G proteins, and adenylyl cyclase activities. |
5(0,0,0,5) | Details |
| 10235294 | Ratsma JE, Gunning WB, Leurs R, Schoffelmeer AN: Platelet adenylyl cyclase activity as a biochemical trait marker for predisposition to alcoholism. Alcohol Clin Exp Res. 1999 Apr;23(4):600-4. |
5(0,0,0,5) | Details |
| 15779331 | Shpakov AO, Korol'kov VI, Plesneva SA, Kuznetsova LA, Pertseva MN: Effects of the C-terminal peptide of the alphaS subunit of the G protein on the regulation of adenylyl cyclase and protein kinase A activities by biogenic amines and glucagon in mollusk and rat muscles. Neurosci Behav Physiol. 2005 Feb;35(2):177-86. |
5(0,0,0,5) | Details |
| 8985310 | Scarpace PJ, Dove J, Matheny M: Effects of age on beta adrenergic subtype activation of adenylyl cyclase in brown adipose tissue. Proc Soc Exp Biol Med. 1996 Dec;213(3):262-7. |
5(0,0,0,5) | Details |
| 8739246 | Kaura D, Takeda N, Sethi R, Wang X, Nagano M, Dhalla NS: Beta-adrenoceptor mediated signal transduction in congestive heart failure in cardiomyopathic (UM-X7.1) hamsters. Mol Cell Biochem. 1996 Apr 12-26;157(1-2):191-6. In view of the lack of information regarding the status of beta-adrenoceptor mediated signal transduction mechanisms at severe stages of congestive heart failure, the status of beta-adrenoceptors, G-proteins and adenylyl cyclase activities was examined in 220-275 day old cardiomyopathic hamster hearts. |
4(0,0,0,4) | Details |
| 9316442 | Mitchell J, Bansal A: Dexamethasone increases G alpha q-11 expression and hormone-stimulated phospholipase C activity in UMR-106-01 cells. Am J Physiol. 1997 Sep;273(3 Pt 1):E528-35. We examined the effect of glucocorticoids on parathyroid hormone (PTH) activation of two G protein-activated signal transduction pathways, phospholipase C (PLC) and adenylyl cyclase, in osteosarcoma UMR-106-01 cells. |
4(0,0,0,4) | Details |
| 8703995 | Pozo D, Segura JJ, Carrero I, Guijarro LG, Prieto JC, Calvo JR: Characterization of adenylyl cyclase stimulated by VIP in rat and mouse peritoneal macrophage membranes. Biochim Biophys Acta. 1996 Jul 24;1312(3):249-54. Other agents like GTP, Gpp (NH) p, GTP-gamma-S, sodium fluoride, and forskolin, at a concentration of 0.1 mM, increased the basal activity of enzyme by 3.1, 5.7, 4.7, 3.6, and 7.8-fold, respectively. |
4(0,0,0,4) | Details |
| 11574818 | Kim SW, Yeum CH, Kim S, Oh Y, Choi KC, Lee J: Amphotericin B decreases adenylyl cyclase activity and aquaporin-2 expression in rat kidney. J Lab Clin Med. 2001 Oct;138(4):243-9. The cAMP generation in response to AVP or sodium fluoride was decreased, whereas that to forskolin was not significantly altered. |
4(0,0,0,4) | Details |
| 12604622 | Gogarten W, Lindeman KS, Hirshman CA, Emala CW: Tumor necrosis factor alpha stimulates adenylyl cyclase activity in human myometrial cells. Biol Reprod. 2003 Mar;68(3):751-7. |
4(0,0,0,4) | Details |
| 8974037 | Bartel S, Karczewski P, Krause EG: G proteins, adenylyl cyclase and related phosphoproteins in the developing rat heart. Mol Cell Biochem. 1996 Oct-Nov;163-164:31-8. |
4(0,0,0,4) | Details |
| 11003581 | Emala CW, Clancy-Keen J, Hirshman CA: Decreased adenylyl cyclase protein and function in airway smooth muscle by chronic carbachol pretreatment. Am J Physiol Cell Physiol. 2000 Oct;279(4):C1008-15. |
4(0,0,0,4) | Details |
| 8754735 | Laglia G, Zeiger MA, Leipricht A, Caturegli P, Levine MA, Kohn LD, Saji M: Increased cyclic 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells. Endocrinology. 1996 Aug;137(8):3170-6. Although levels of immunoreactive Gq alpha and Gq alpha 11 were normal in TG8 cells, sodium fluoride-induced [3H] IP production was also inhibited. Thyroid cell growth and function are regulated by several hormones and growth factors that bind to cell surface receptors coupled via G proteins, Gs and Gq, to stimulation of adenylyl cyclase and phospholipase C (PLC), respectively. |
3(0,0,0,3) | Details |
| 12054468 | Boumati M, Li Y, Anand-Srivastava MB: Modulation of ANP-C receptor signaling by endothelin-1 in A-10 smooth muscle cells. Arch Biochem Biophys. 2002 May 15;401(2):178-86. We have previously shown that pretreatment of A-10 smooth muscle cells (SMC) with angiotensin II (Ang II) attenuated atrial natriuretic peptide (ANP) receptor-C (ANP-C)-mediated inhibition of adenylyl cyclase without altering (125) I-ANP binding. |
4(0,0,0,4) | Details |
| 8804072 | Reddy PL, Bhargava HN: Effect of low pH treatment on opioid peptides binding to their receptors and functional coupling of G-proteins to adenylyl cyclase in the rat spinal cord. Peptides. 1996;17(4):625-8. Because low pH treatment is known to alter the coupling of G-proteins to brain receptors, and little is known about such an effect in the spinal cord, the present study was undertaken to examine whether preincubation of rat spinal cord membranes at low pH (pH 4.5) alters opioid receptor binding characteristics and sodium fluoride (NaF)-stimulated adenylyl cyclase (AC) activity (as a function of G, mediated). [3H][D-Ala2,MePhe4,Gly-ol] enkephalin (DAMGO) and [3H] ethylketocyclazosine (EKC) were used to label mu- and kappa-opioid receptors, respectively. |
82(1,1,1,2) | Details |
| 12745716 | Yeum CH, Kim SW, Lee SC, Choi KC, Ahn KY, Lee J: Diminished expression of aquaporin water channels in ureteral-obstructed kidney in rats. Scand J Urol Nephrol. 2003;37(2):99-105. The expression of AQP1 and AQP3 was decreased in the outer medulla and inner medulla. cAMP generation in response to AVP, sodium fluoride or forskolin was greatly decreased. In order to specifically determine primary impairment of the pathway leading to an altered regulation of AQP channels stimulated by the arginine vasopressin (AVP)/cyclic (cAMP) pathway, the catalytic activity and protein expression of different parts of the adenylyl cyclase complex were separately determined. |
3(0,0,0,3) | Details |
| 11003579 | Di Fusco F, Hashim S, Anand-Srivastava MB: Volume overload cardiac hypertrophy exhibits decreased expression of g (s) alpha and not of g (i) alpha in heart. Am J Physiol Cell Physiol. 2000 Oct;279(4):C990-8. Cardiac hypertrophy in Sprague-Dawley rats (200-250 g) was induced under anesthesia, and, after a period of 10 days, the hearts were used for adenylyl cyclase activity determination, protein quantification, and mRNA level determination. |
3(0,0,0,3) | Details |
| 9176218 | Im DS, Fujioka T, Katada T, Kondo Y, Ui M, Okajima F: Characterization of -induced actions and its signaling pathways in rat hepatocytes. Am J Physiol. 1997 May;272(5 Pt 1):G1091-9. Pertussis toxin treatment almost completely suppressed the S-1-P-induced inhibition of adenylyl cyclase but hardly influenced the lipid-induced activation of PLC and its cascade reactions. |
2(0,0,0,2) | Details |
| 9212031 | Sun LS, Du F, Quaegebeur JM: Right ventricular infundibular beta-adrenoceptor complex in tetralogy of Fallot patients. Pediatr Res. 1997 Jul;42(1):12-6. Surgically excised right ventricular infundibular myocardial specimens from symptomatic (patients with spells) and asymptomatic patients were used to determine total beta1 and beta2 betaAR density and betaAR adenylyl cyclase activity. |
2(0,0,0,2) | Details |
| 8972723 | Di Stefano A, La Gaetana R, Bovalini L, Lusini P, Martelli P: Pertussis toxin reverses the inhibition of the adenylyl cyclase system by khellin in HeLa cells. Biochim Biophys Acta. 1996 Nov 8;1314(1-2):105-8. |
2(0,0,0,2) | Details |
| 20141037 | Derkach KV, Shpakov AO, Uspenskaia ZI, Kuznetsova LA: [Inhibition of the adenylyl cyclase signaling system by colchicine and vinblastine in ciliate Dileptus anser]. Tsitologiia. 2009;51(12):1013-8. The treatment of D. anser with colchicine and vinblastine (10 (-5)-10 (-6) M) weakly influenced basal activity of AC, but caused essential decrease or complete blocking of AC stimulation by non-hormonal (GppNHp, sodium fluoride) and hormonal (aldrenaline, glucagon) agents. |
2(0,0,0,2) | Details |
| 11029293 | Pei JM, Yu XC, Fung ML, Zhou JJ, Cheung CS, Wong NS, Leung MP, Wong TM: Impaired G (s) alpha and adenylyl cyclase cause beta-adrenoceptor desensitization in chronically hypoxic rat hearts. Am J Physiol Cell Physiol. 2000 Nov;279(5):C1455-63. |
2(0,0,0,2) | Details |
| 10505332 | Shpakov AO, Derkach KV: [The role of sulfhydryl groups in functioning of components of adenylate cyclase signal system in smooth muscles of the mollusk Anodonta cygnea (effect of N-ethylmaleimide and p-chloromercuribenzoic acid)]. Tsitologiia. 1999;41(6):499-505. The alkylating agent N-ethylameimide and the sulfhydryl group blocker p-chloromercuribenzoic acid (CPMA) inhibited in dose-dependent manner both basal activity of adenylyl cyclase (AC) and its activity stimulated by non-hormonal substances (forskolin, sodium fluoride, guanylilimidodiphosphate) in smooth muscles of the freshwater bivalve mollusk Anodonta cygnea. |
32(0,1,1,2) | Details |
| 12552211 | Lee TW, Grocott HP, Schwinn D, Jacobsohn E: High spinal anesthesia for cardiac surgery: effects on beta-adrenergic receptor function, stress response, and hemodynamics. Anesthesiology. 2003 Feb;98(2):499-510. RESULTS: In patients with cardiopulmonary bypass (CPB) times in excess of 1 h, the ITB group had significantly less atrial beta-receptor dysfunction, as measured by maximal isproteronol, 50% maximal isoproterenol, sodium fluoride-stimulated activity, and zinterol stimulation assays of adenylyl cyclase activity (P < or = 0.02) and beta-adrenergic receptor density (P = 0.02). |
31(0,1,1,1) | Details |
| 15579502 | Kim SW, Kim JW, Choi KC, Ma SK, Oh Y, Jung JY, Kim J, Lee J: Indomethacin enhances shuttling of aquaporin-2 despite decreased abundance in rat kidney. J Am Soc Nephrol. 2004 Dec;15(12):2998-3005. The generation of cAMP provoked by arginine vasopressin, sodium fluoride, or forskolin was blunted. The activity of adenylyl cyclase complexes was determined by stimulated accumulation of cAMP. |
2(0,0,0,2) | Details |
| 9015861 | Grasso P: Functional reconstitution of detergent-solubilized bovine calf testis luteinizing hormone/chorionic gonadotropin receptor into phospholipid vesicles. Recept Signal Transduct. 1996;6(2):53-62. The reconstituted receptor was functionally coupled to adenylyl cyclase and responded to both LH and NaF with increased cyclic AMP (cAMP) production. Similar uptake could not be induced by sodium fluoride, (Bu) 2 cAMP, GTP-gamma-S, cholera toxin, or pertussis toxin. |
2(0,0,0,2) | Details |
| 16998537 | Ge C, Garcia R, Anand-Srivastava MB: Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats. Can J Physiol Pharmacol. 2006 Jul;84(7):739-46. |
2(0,0,0,2) | Details |
| 9743395 | Booth JV, Landolfo KP, Chesnut LC, Bennett-Guerrero E, Gerhardt MA, Atwell DM, El-Moalem HE, Smith MS, Funk BL, Kuhn CM, Kwatra MM, Schwinn DA: Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Anesthesiology. 1998 Sep;89(3):602-11. Plasma catecholamine concentrations, myocardial betaAR density, and functional responsiveness (basal, isoproterenol, zinterol, sodium fluoride, and -stimulated adenylyl cyclase activity) were assessed. |
12(0,0,1,7) | Details |
| 8927025 | Anand-Srivastava MB, McNeill JH, Yang XP: Reversal of defective G-proteins and adenylyl cyclase/cAMP signal transduction in diabetic rats by vanadyl sulphate therapy. Mol Cell Biochem. 1995 Dec 6-20;153(1-2):113-9. The basal enzyme activity, as well as the stimulatory effects of nucleotides, glucagon, N-Ethylcarboxamideadenosine (NECA), isoproterenol, forskolin and sodium fluoride (NaF) on adenylyl cyclase were significantly increased in STZ-D rat liver as compared to control. |
12(0,0,1,7) | Details |
| 11316845 | Kim SW, Lee JU, Nah MY, Kang DG, Ahn KY, Lee HS, Choi KC: Cisplatin decreases the abundance of aquaporin water channels in rat kidney. J Am Soc Nephrol. 2001 May;12(5):875-82. However, the cyclic generation in response to forskolin was not affected, whereas that to sodium fluoride was diminished significantly. To specify further the primary point of derangement in the pathway that activates the arginine vasopressin-mediated AQP channels, different components of adenylyl cyclase complex were examined separately. |
1(0,0,0,1) | Details |
| 12950106 | Baxendale RW, Fraser LR: Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa. Mol Reprod Dev. 2003 Oct;66(2):181-9. |
1(0,0,0,1) | Details |
| 15201623 | Sethi R, Wang X, Ferrari R, Dhalla NS: Improvement of cardiac function and beta-adrenergic signal transduction by propionyl in congestive heart failure due to myocardial infarction. Coron Artery Dis. 2004 Feb;15(1):65-71. Crude membranes were isolated from the remote, nonischemic (viable) left ventricle and examined for changes in beta-AR and adenylyl cyclase (AC) activity. The stimulation of AC activities with isoproterenol, 5'-guanyl imidodiphosphate, forskolin and sodium fluoride was decreased in the failing hearts and these changes were also prevented by PLC treatment. |
1(0,0,0,1) | Details |