Protein Information

Name thrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
1115776 Muenzer J, Weinbach EC, Wolfe SM: Oxygen consumption of human blood platelets. Biochim Biophys Acta. 1975 Feb 17;376(2):243-8.

Effect of inhibitors on thrombin-induced oxygen burst..
Similar differential inhibitory effects were observed with oligomycin, antimycin, rotenone and N-ethylmaleimide.
5(0,0,0,5) Details
18439569 Lopez JJ, Jardin I, Bobe R, Pariente JA, Enouf J, Salido GM, Rosado JA: STIM1 regulates acidic Ca2+ store refilling by interaction with SERCA3 in human platelets. Biochem Pharmacol. 2008 Jun 1;75(11):2157-64. Epub 2008 Mar 22.


Electrotransjection of cells with anti-STIM1 (Y (231)-K (243)) antibody, directed towards a cytoplasmic sequence of STIM1, significantly reduced acidic store refilling, which was tested by remobilizing Ca (2+) from the acidic stores using 2,5-di-(t-butyl)-1,4-hydroquinone (TBHQ) after a brief refilling period that followed thrombin stimulation.
3(0,0,0,3) Details