Protein Information

Name GRP78
Synonyms 78 kDa glucose regulated protein; MIF 2; MIF2; 78 kDa glucose regulated protein precursor; BIP; Endoplasmic reticulum lumenal Ca(2+) binding protein grp78; GRP 78; GRP78…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
18508033 Chen YY, Chen G, Fan Z, Luo J, Ke ZJ: GSK3beta and endoplasmic reticulum stress mediate rotenone-induced death of SK-N-MC neuroblastoma cells. Biochem Pharmacol. 2008 Jul 1;76(1):128-38. Epub 2008 Apr 29.

Rotenone also induced endoplasmic reticulum (ER) stress which was evident by an increase in phosphorylation of PERK, PKR, and eIF2alpha as well as the expression of GRP78.
31(0,1,1,1) Details