| Name | NDUFA1 |
|---|---|
| Synonyms | CI MWFE; Complex I MWFE; MWFE; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; NADH ubiquinone oxidoreductase 1 alpha subcomplex 1; NADH ubiquinone oxidoreductase MWFE subunit; NDUFA 1; NDUFA1… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10200266 | Au HC, Seo BB, Matsuno-Yagi A, Yagi T, Scheffler IE: The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4354-9. Complementation with hamster NDUFA1 cDNA restored the rotenone-sensitive complex I activity of these mutant cells to approximately 100% of the parent cell activity. |
12(0,0,1,7) | Details |
| 12758076 | Marques I, Duarte M, Videira A: The 9.8 kDa subunit of complex I, related to bacterial Na (+)-translocating NADH dehydrogenases, is required for enzyme assembly and function in Neurospora crassa. J Mol Biol. 2003 May 30;329(2):283-90. A nuclear gene encoding a 9.8 kDa subunit of complex I, the homologue of mammalian MWFE protein, was identified in the genome of Neurospora crassa. Respiration of mutant mitochondria on matrix is rotenone-insensitive, confirming that the 9.8 kDa protein is required for the assembly and activity of complex I. |
2(0,0,0,2) | Details |