| Name | CHOP |
|---|---|
| Synonyms | 75 kDa DNA pairing protein; FUS1; CHOP; FUS; FUS 1; FUS CHOP; FUS/ATF1fusion gene; FUS/CHOP fusion gene… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19233273 | Silva JM, Wong A, Carelli V, Cortopassi GA: Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia. Neurobiol Dis. 2009 May;34(2):357-65. Epub 2009 Feb 20. The same doses of rotenone that reduced ATP production also induced dose-dependent increases in PERK and eIF2alpha phosphorylation as well as activated the ISR stress genes, ATF4 and CHOP. |
31(0,1,1,1) | Details |
| 19304788 | Ishikawa F, Akimoto T, Yamamoto H, Araki Y, Yoshie T, Mori K, Hayashi H, Nose K, Shibanuma M: Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain. J Biochem. 2009 Jul;146(1):123-32. Epub 2009 Mar 20. In this study, changes in gene expression resulting from pharmacological inhibition of the respiratory chain were studied by DNA microarray analysis using cells treated with rotenone or antimycin A, which inhibit complexes I and III of the electron transport system, respectively. |
7(0,0,0,7) | Details |
| 18508033 | Chen YY, Chen G, Fan Z, Luo J, Ke ZJ: GSK3beta and endoplasmic reticulum stress mediate rotenone-induced death of SK-N-MC neuroblastoma cells. Biochem Pharmacol. 2008 Jul 1;76(1):128-38. Epub 2008 Apr 29. Rotenone had a modest effect on the expression of CHOP. |
6(0,0,1,1) | Details |
| 17276738 | Fujita Y, Ito M, Nozawa Y, Yoneda M, Oshida Y, Tanaka M: CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations. Mitochondrion. 2007 Feb-Apr;7(1-2):80-8. Epub 2006 Dec 3. |
5(0,0,0,5) | Details |
| 12111836 | Conn KJ, Gao WW, Ullman MD, McKeon-O'Malley C, Eisenhauer PB, Fine RE, Wells JM: Specific up-regulation of GADD153/CHOP in 1-methyl-4-phenyl-pyridinium-treated SH-SY5Y cells. J Neurosci Res. 2002 Jun 15;68(6):755-60. Comparison of GADD153 expression among cultures treated with other toxins whose primary mode of action is either via mitochondrial impairment (rotenone) or via oxidative stress or peroxide) showed that GADD153 was uniquely up-regulated by MPP (+). |
1(0,0,0,1) | Details |