Name | NDUFS3 |
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Synonyms | CI 30KD; Complex I 30KD; NADH dehydrogenase (ubiquinone) Fe S protein 3 (30kD) (NADH coenzyme Q reductase); NADH ubiquinone oxidoreductase 30 kDa subunit; NADH ubiquinone oxidoreductase Fe S protein 3; NDUFS 3; NDUFS3; Complex I 30KDs… |
Name | rotenone |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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18485875 | Martinvalet D, Dykxhoorn DM, Ferrini R, Lieberman J: Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death. Cell. 2008 May 16;133(4):681-92. Here we find that GzmA accesses the mitochondrial matrix to cleave the complex I protein NDUFS3, an iron- subunit of the NADH:ubiquinone oxidoreductase complex I, after Lys56 to interfere with oxidation and generate anions. |
2(0,0,0,2) | Details |