Protein Information

Name beta is
Synonyms "beta I"; Alpha II; Alpha tryptase; Beta I; Lung tryptase; Mast cell protease II; Mast cell tryptase; Pituitary tryptase…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
8299570 Sauer LA, Chapman JC, Dauchy RT: Topology of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4-isomerase in adrenal cortex mitochondria and microsomes. Endocrinology. 1994 Feb;134(2):751-9.

Mitochondrial 3 beta HSD activity may be enhanced by oxidation of intermembrane space NADH via an active rotenone- and antimycin-a-insensitive NADH oxidase.
3 beta-Hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4-isomerase (3 beta HSD) is a NAD (+)-dependent membrane-bound enzyme that catalyzes the oxidation of delta 5-3 beta-hydroxysteroids to delta 4-3-keto structures during adrenal, gonadal, and placental steroidogenesis.
2(0,0,0,2) Details
2561442 Stephenson G, Sanadi DR: Evidence that coupling factor B is bound to the matrix side of the inner mitochondrial membrane. Biochem Int. 1989 Nov;19(5):1087-94.

Rotenone-sensitive NADH dehydrogenase activity and Lubrol stimulation of cytochrome oxidase activity were measured to assess the opposite membrane polarity of beef heart mitoplast and inside-out particle preparations.
From these results it is concluded that in beef heart mitochondria, the coupling factor F beta is bound to the matrix-side of the inner mitochondrial membrane.
1(0,0,0,1) Details