| Name | calcium channel (protein family or complex) |
|---|---|
| Synonyms | calcium channel |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9560449 | Hernandez-Guijo JM, de Pascual R, Garcia AG, Gandia L: Separation of calcium channel current components in mouse chromaffin cells superfused with low- and high-barium solutions. Pflugers Arch. 1998 Jun;436(1):75-82. When using 2 mM Ba2+ as the charge carrier, nifedipine (3 microM) blocked IBa by 40-45%. omega-Conotoxin GVIA (1 microM) caused 26% inhibition, while omega-conotoxin MVIIC (3 microM) produced a 48% blockade. |
1(0,0,0,1) | Details |
| 2423956 | McDonald TF, Cavalie A, Trautwein W, Pelzer D: Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes. Pflugers Arch. 1986 May;406(5):437-48. Average currents (I) calculated from ensembles of records of single Ca channel current had voltage-dependent time courses resembling those of whole-cell IBa (90 mM). 6. |
1(0,0,0,1) | Details |
| 9463438 | Adams DJ, Trequattrini C: Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons. J Neurophysiol. 1998 Feb;79(2):753-62. Half-maximal inhibition of Ba2+ current (IBa) amplitude was obtained with 270 nM Met-enkephalin or Leu-enkephalin. |
1(0,0,0,1) | Details |
| 9380037 | Ito H, Klugbauer N, Hofmann F: Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel. Mol Pharmacol. 1997 Oct;52(4):735-40. The chimeras were transiently expressed in human embryonic kidney 293 cells and the whole-cell Ba2+ current (IBa) was recorded. |
1(0,0,0,1) | Details |
| 9335409 | Zhang S, Sawanobori T, Hirano Y, Hiraoka M: Multiple modulations of action potential duration by different calcium channel blocking agents in guinea pig ventricular myocytes. J Cardiovasc Pharmacol. 1997 Oct;30(4):489-96. Whereas Mn2+ suppressed IBa without changing its decay time course, and nisoldipine speeded up the IBa decay with suppressed amplitude of IBa. |
1(0,0,0,1) | Details |
| 7545281 | Gandia L, Borges R, Albillos A, Garcia AG: Multiple calcium channel subtypes in isolated rat chromaffin cells. Pflugers Arch. 1995 May;430(1):55-63. Ba2+ currents (IBa) showed variable sensitivity to dihydropyridine (DHP) Ca2+ channel agonists and antagonists. |
1(0,0,0,1) | Details |
| 7491257 | Zong X, Schreieck J, Mehrke G, Welling A, Schuster A, Bosse E, Flockerzi V, Hofmann F: On the regulation of the expressed L-type calcium channel by cAMP-dependent phosphorylation. Pflugers Arch. 1995 Jul;430(3):340-7. The peak Ba2+ current (IBa) of these cells was not affected significantly by internal dialysis with 0.1 mM cAMP-dependent protein kinase inhibitor peptide (mPKI), 25 microM cAMP-dependent protein kinase catalytic subunit (PKA), or a combination of 25 microM PKA and 1 microM okadaic acid. |
1(0,0,0,1) | Details |
| 1279162 | Dascal N, Lotan I, Karni E, Gigi A: Calcium channel currents in Xenopus oocytes injected with rat skeletal muscle RNA. J Physiol. 1992 May;450:469-90. Ba2+ currents (IBa) through voltage-dependent Ca2+ channels were studied in Xenopus laevis oocytes injected with heterologous RNA extracted from skeletal muscle (SkM) of young rats, using the two-electrode voltage clamp technique. 2. |
1(0,0,0,1) | Details |
| 9013606 | Soldatov NM, Zuhlke RD, Bouron A, Reuter H: Molecular structures involved in L-type calcium channel inactivation. J Biol Chem. 1997 Feb 7;272(6):3560-6. Unlike alpha1C,77 and alpha1C,72, Ba2+ currents (IBa) through alpha1C,86 inactivated 8-10 times faster at +20 mV, and its inactivation rate was strongly voltage-dependent. |
1(0,0,0,1) | Details |
| 8183255 | Church J, Fletcher EJ, Abdel-Hamid K, MacDonald JF: blocks high-voltage-activated channels and -evoked responses in rat and mouse cultured hippocampal pyramidal neurons. Mol Pharmacol. 1994 Apr;45(4):747-57. The effects of the antidiarrheal agent on high-voltage-activated (HVA) calcium channel activity and excitatory amino acid-evoked responses in two preparations of cultured hippocampal pyramidal neurons were examined. Voltage-activated Ca2+ channel currents carried by barium ions (IBa) could be discriminated pharmacologically into nifedipine-sensitive (L-type) and nifedipine-resistant, omega-CgTx-sensitive (N-type) components. |
1(0,0,0,1) | Details |
| 10455329 | Unno T, Komori S, Ohashi H: Microtubule cytoskeleton involvement in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle. Br J Pharmacol. 1999 Aug;127(7):1703-11. Effects of agents, which affect microtubule polymerization-depolymerization cycle, on Ba2+ current (IBa) flowing through voltage-gated Ca2+ channels and carbachol (CCh)-induced sustained suppression of IBa were examined in whole-cell voltage-clamped smooth muscle cells of guinea-pig ileum. 2. offchicine (100 microM) and vinblastine (100 microM), microtubule depolymerizers, increased the ampitude of IBa. |
1(0,0,0,1) | Details |
| 8772132 | Tiaho F, Nerbonne JM: VIP and secretin augment cardiac L-type calcium channel currents in isolated adult rat ventricular myocytes. Pflugers Arch. 1996 Sep;432(5):821-30. Using the whole-cell patch-clamp technique, we show here that VIP enhances Ca2+ and Ba2+ currents (IBa) through voltage-dependent L-type Ca2+ channels in adult rat ventricular myocytes. |
1(0,0,0,1) | Details |
| 8662622 | Doring F, Degtiar VE, Grabner M, Striessnig J, Hering S, Glossman H: Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A. J Biol Chem. 1996 May 17;271(20):11745-9. The corresponding barium currents (IBa) were tested for PAA sensitivity during trains of depolarizing test pulses (conditioned block). |
1(0,0,0,1) | Details |
| 2455273 | Hering S, Beech DJ, Bolton TB, Lim SP: Action of nifedipine or BAY K8644 is dependent on calcium channel state in single smooth muscle cells from rabbit ear artery. Pflugers Arch. 1988 May;411(5):590-2. Nifedipine (3 microM) caused a reduction in the barium current (IBa) evoked by steps to potentials positive of -10 mV. |
1(0,0,0,1) | Details |
| 7511687 | Jassar BS, Pennefather PS, Smith PA: Changes in and calcium channel activity following axotomy of B-cells in bullfrog sympathetic ganglion. J Physiol. 1993 Dec;472:203-31. Currents mediated by Ca2+ channels using Ba2+ as a charge carrier (IBa), Na+ currents (INa) and voltage- and Ca (2+)-dependent K+ currents (IC) were recorded from bullfrog paravertebral sympathetic ganglion B-cells using whole-cell patch-clamp recording techniques. |
1(0,0,0,1) | Details |
| 8718981 | Aggarwal R, Boyden PA: Altered pharmacologic responsiveness of reduced L-type currents in myocytes surviving in the infarcted heart. J Cardiovasc Electrophysiol. 1996 Jan;7(1):20-35. Furthermore, application of forskolin (1 micro M and 10 micro M) or intracellular cAMP (200 micro M), agents known to act downstream of the beta-receptor, also produced a smaller increase in peak IBa density in IZs versus NZs, suggesting that multiple defects exist in the beta-adrenergic signaling pathway of IZs. The pharmacologic responses of macroscopic L-type calcium channel currents to the dihydropyridine agonist, Bay K 8644, and beta-adrenergic receptor stimulation by isoproterenol were studied in myocytes enzymatically dissociated from the epicardial border zone of the arrhythmic 5-day infarcted canine heart (IZs). |
1(0,0,0,1) | Details |
| 10482914 | Ogura T, Jones S, Shuba LM, McCullough JR, McDonald TF: Block and modified gating of cardiac calcium channel currents by terodiline. Br J Pharmacol. 1999 Aug;127(8):1837-45. |
1(0,0,0,1) | Details |
| 1326744 | Dolphin AC: The effect of phosphatase inhibitors and agents increasing cyclic-AMP-dependent phosphorylation on calcium channel currents in cultured rat dorsal root ganglion neurones: interaction with the effect of G protein activation. Pflugers Arch. 1992 Jun;421(2-3):138-45. The amplitude of IBa (GTP gamma S), recorded in the presence of GTP [ gamma S] (200 microM) in the patch pipette solution, is enhanced by external application of forskolin (10 microM), and there is an increase in the proportion of the rapidly activating component of the current. |
1(0,0,0,1) | Details |
| 8389058 | Yao Y, Zhu H, Yang YS, Bao YD: [A voltage-clamp study on voltage-gated channels translated in Xenopus oocytes by rat brain mRNA]. Sheng Li Xue Bao. 1993 Feb;45(1):44-54. L-type calcium channel ligands, nifedipine and Bay K 8644 inhibited IBa at 100 mumol/L, while another dihydropyridine ligand (+/-) nimodipine enhanced IBa at the same concentration. |
81(1,1,1,1) | Details |
| 7623277 | Unno T, Komori S, Ohashi H: Inhibitory effect of muscarinic receptor activation on Ca2+ channel current in smooth muscle cells of guinea-pig ileum. J Physiol. 1995 May 1;484 ( Pt 3):567-81. A calcium channel current (IBa), when Ba2+ was used as a charge carrier, was also suppressed by CCh in a biphasic manner, as with ICa. |
34(0,1,1,4) | Details |
| 2541856 | Dolphin AC, McGuirk SM, Scott RH: An investigation into the mechanisms of inhibition of calcium channel currents in cultured sensory neurones of the rat by nucleotide analogues and (-)-baclofen. Br J Pharmacol. 1989 May;97(1):263-73. The inhibition by GTP-gamma-S is particularly characterized by an abolition of the transient component of calcium channel currents carried either by Ba2+ (IBa) or by Ca2+ (ICa). 2. |
33(0,1,1,3) | Details |
| 9325359 | Cuevas J, Adams DJ: M4 muscarinic receptor activation modulates calcium channel currents in rat intracardiac neurons. J Neurophysiol. 1997 Oct;78(4):1903-12. The dose-response relationship obtained for -induced inhibition of Ba2+ current (IBa) exhibited a half-maximal inhibition at 6 nM. |
1(0,0,0,1) | Details |
| 8046455 | Zong X, Lux HD: Augmentation of calcium channel currents in response to G protein activation by GTP gamma S in chick sensory neurons. J Neurosci. 1994 Aug;14(8):4847-53. The Ba2+ current (IBa) showed an absolute enhancement by a factor near 2, 15 min after GTP gamma S application. |
1(0,0,0,1) | Details |
| 9300300 | Mitcheson JS, Hancox JC, Levi AJ: Cultured adult rabbit myocytes: effect of adding supplements to the medium, and response to isoprenaline. J Cardiovasc Electrophysiol. 1997 Sep;8(9):1020-30. INTRODUCTION: The aims of this study were to investigate: (1) the effect of supplementing the culture medium on preservation of L-type calcium channel current (1Ca,L) in adult rabbit ventricular myocytes cultured for 4 days; and (2) preservation of the ICa,L response in cultured myocytes to the beta-adrenergic agonist isoprenaline. |
1(0,0,0,1) | Details |
| 10323586 | Connor M, Schuller A, Pintar JE, Christie MJ: Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1. Br J Pharmacol. 1999 Apr;126(7):1553-8. The actions of opioid receptor agonists on the calcium channel currents (IBa) of acutely dissociated periaqueductal grey (PAG) neurons from C57B16/J mice and mutant mice lacking the first exon of the mu-opioid receptor (MOR-1) were examined using whole cell patch clamp techniques. |
32(0,1,1,2) | Details |
| 1653319 | Dolphin AC: Ca2+ channel currents in rat sensory neurones: interaction between nucleotides, cyclic AMP and Ca2+ channel ligands. J Physiol. 1991 Jan;432:23-43. The calcium channel antagonist (-)-202-791 (5 microM) increased the amplitude of IBa, GTP gamma S when applied at VH -80 mV, but either not, or only transiently, at VH -30 mV, as previously observed. |
32(0,1,1,2) | Details |
| 10602337 | Connor M, Borgland SL, Christie MJ: Continued morphine modulation of calcium channel currents in acutely isolated locus coeruleus neurons from morphine-dependent rats. Br J Pharmacol. 1999 Dec;128(7):1561-9. The actions of the opioid agonists morphine and -enkephalin (met-enkephalin) on the calcium channel currents (IBa) of acutely isolated locus coeruleus (LC) neurons from morphine-dependent and vehicle-treated rats were examined using whole cell patch clamp techniques. 2. |
32(0,1,1,2) | Details |
| 9547377 | Stephens GJ, Brice NL, Berrow NS, Dolphin AC: Facilitation of rabbit alpha1B channels: involvement of endogenous Gbetagamma subunits. J Physiol. 1998 May 15;509 ( Pt 1):15-27. Co-expression of the Gbeta1gamma2 subunit, together with the alpha1B/alpha2-delta/beta2a calcium channel combination, resulted in a marked degree of depolarizing prepulse-reversible inhibition of the whole-cell ICa or IBa. |
32(0,1,1,2) | Details |
| 2433043 | Ikemoto Y, Mitsuiye T, Ishizuka S: Reduction of the voltage-dependent current in Aplysia neurons by pentobarbital. Cell Mol Neurobiol. 1986 Sep;6(3):293-305. When was replaced with barium ion in the perfusing solution, in which neither nor ions carried transmembrane currents, the barium current (IBa) which flowed through the calcium channel of the cell membrane was generated by depolarizing pulses of several hundred milliseconds applied every 1 min from a holding potential of -50 mV. |
0(0,0,0,0) | Details |
| 8309795 | Menon-Johansson AS, Berrow N, Dolphin AC: G (o) transduces GABAB-receptor modulation of N-type channels in cultured dorsal root ganglion neurons. Pflugers Arch. 1993 Nov;425(3-4):335-43. High-voltage-activated (HVA) calcium channel currents (IBa) were recorded from acutely replated cultured dorsal root ganglion (DRG) neurons. |
31(0,1,1,1) | Details |
| 11474650 | Petrov T, Shapiro Y, Baker C, Duff JP, Sanders EJ, Gordon T, Smith PA: Peripheral target contact regulates Ca2+ channels in the cell bodies of bullfrog sympathetic ganglion B-neurons. Auton Neurosci. 2001 Jun 20;89(1-2):74-85. Calcium channel current in ganglionic B-neurons, (measured at -10 mV; holding potential -60 mnV; Ba2+ as charge carrier; IBa) was reduced. |
31(0,1,1,1) | Details |
| 8603123 | Hughes AD, Parkinson NA, Wijetunge S: alpha2-Adrenoceptor activation increases calcium channel currents in single vascular smooth muscle cells isolated from human omental resistance arteries. J Vasc Res. 1996 Jan-Feb;33(1):25-31. Calcium channel currents (IBa) were recorded using whole cell voltage clamp techniques with Ba2+ as the charge carrier. |
7(0,0,1,2) | Details |
| 10618676 | Clunn GF, Wijetunge S, Hughes AD: Effect of hypercholesterolaemia on voltage-operated calcium channel currents in rabbit arterial smooth muscle cells. J Hum Hypertens. 1999 Dec;13(12):849-53. In this study calcium channel currents (IBa) were compared using conventional whole cell voltage clamp techniques in ear artery cells isolated from control New Zealand White rabbits (NZ) with those from WHHL. |
7(0,0,1,2) | Details |
| 10420008 | Magistretti J, Brevi S, de Curtis M: Biophysical and pharmacological diversity of high-voltage-activated currents in layer II neurones of guinea-pig piriform cortex. J Physiol. 1999 Aug 1;518 ( Pt 3):705-20. The P/Q-type calcium channel blockers omega-agatoxin IVA (100 nM), omega-conotoxin MVIIC (1 microM) and 3.3 funnel toxin (1 microM), had little effect on IBa. 5. |
7(0,0,1,2) | Details |
| 9211820 | Xu WX, Kim SJ, So I, Kim KW: Role of actin microfilament in osmotic stretch-induced increase of voltage-operated calcium channel current in guinea-pig gastric myocytes. Pflugers Arch. 1997 Aug;434(4):502-4. Using the whole-cell patch clamp technique, the role of actin microfilament in hyposmotic increase of voltage-operated calcium channel current (IBa) was studied in guinea-pig gastric myocytes. |
7(0,0,1,2) | Details |
| 9547380 | Connor M, Christie MJ: Modulation of Ca2+ channel currents of acutely dissociated rat periaqueductal grey neurons. J Physiol. 1998 May 15;509 ( Pt 1):47-58. The actions of the neuropeptide nociceptin on the calcium channel currents (IBa) of acutely dissociated rat periaqueductal grey (PAG) neurons were examined using whole-cell patch clamp techniques. |
6(0,0,1,1) | Details |
| 8308719 | Campbell V, Berrow N, Dolphin AC: GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G (0): antisense oligonucleotide studies. J Physiol. 1993 Oct;470:1-11. Calcium channel currents (IBa) were recorded in cultured dorsal root ganglion neurones (DRGs), 24-32 h after microinjection with 20-mer phosphorothioate antisense oligonucleotides complementary either to a G alpha o or a G alpha i unique sequence, or with a nonsense sequence. 2. |
6(0,0,1,1) | Details |
| 2460176 | Scott RH, McGuirk SM, Dolphin AC: Modulation of divalent cation-activated ion currents. Br J Pharmacol. 1988 Jul;94(3):653-62. Voltage-sensitive calcium channel currents carried by Ca2+ (ICa) or Ba2+ (IBa) were followed by tail currents carried by Cl- ions in approximately 45% of cultured dorsal root ganglion neurones. 2. |
6(0,0,1,1) | Details |
| 7738844 | Pearson HA, Sutton KG, Scott RH, Dolphin AC: Characterization of Ca2+ channel currents in cultured rat cerebellar granule neurones. J Physiol. 1995 Feb 1;482 ( Pt 3):493-509. High-threshold voltage-gated calcium channel currents (IBa) were studied in cultured rat cerebellar granule neurones using the whole-cell patch clamp technique with 10 mM Ba2+ as the charge carrier. |
6(0,0,1,1) | Details |
| 7761264 | Welling A, Lacinova L, Donatin K, Ludwig A, Bosse E, Flockerzi V, Hofmann F: Expression of the L-type calcium channel with two different beta subunits and its modulation by Ro 40-5967. Pflugers Arch. 1995 Jan;429(3):400-11. Ro 40-5967 decreased isradipine binding by an apparent allosteric interaction and blocked the barium inward currents (IBa) in a voltage- and use-dependent manner in all cells. |
4(0,0,0,4) | Details |
| 6262507 | Krishtal OA, Pidoplichko VI, Shakhovalov YA: Conductance of the calcium channel in the membrane of snail neurones. J Physiol. 1981 Jan;310:423-34. Its value for the transfer of Ba2+ ions is iBa = 0.20 +/- 0.02 pA (S.E.). |
4(0,0,0,4) | Details |
| 8120832 | Welling A, Bosse E, Cavalie A, Bottlender R, Ludwig A, Nastainczyk W, Flockerzi V, Hofmann F: Stable co-expression of calcium channel alpha 1, beta and alpha 2/delta subunits in a somatic cell line. J Physiol. 1993 Nov;471:749-65. The co-expression of the alpha 1 subunit with the beta subunit (CaB1 gene) enhanced the density of the dihydropyridine binding sites 2- to 3-fold and increased dihydropyridine-sensitive barium inward currents (IBa) up to 3.5-fold from -13.3 microA/cm2 (alpha 1 subunit) to -46.7 microA/cm2 (alpha 1 and beta subunits). 4. |
3(0,0,0,3) | Details |
| 10087148 | Klugbauer N, Marais E, Lacinova L, Hofmann F: A T-type calcium channel from mouse brain. . Pflugers Arch. 1999 Apr;437(5):710-5. In contrast to L-type calcium channel currents, IBa and ICa through the alpha1G channel expressed in HEK293 cells did not differ in terms of current density, voltage dependence of current activation, inactivation and deactivation, and speed of recovery from voltage-dependent inactivation. |
3(0,0,0,3) | Details |
| 9660896 | Shen W, Slaughter MM: Metabotropic and ionotropic glutamate receptors regulate calcium channel currents in salamander retinal ganglion cells. J Physiol. 1998 Aug 1;510 ( Pt 3):815-28. suppressed high-voltage-activated barium currents (IBa, HVA) in tiger salamander retinal ganglion cells. |
3(0,0,0,3) | Details |
| 8886400 | Unno T, Komori S, Ohashi H: Some evidence against the involvement of in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle cells. Br J Pharmacol. 1996 Sep;119(2):213-22. In cells bathed in Ba2+ PSS and dialysed with Cs (+)-based low EGTA (0.05 mM) pipette solution, and in which Ba2+ current (IBa) flowing through voltage-gated channels was evoked repeatedly by stepping to 0 mV from the holding potential of -60 mV, AA (1-30 microM), applied extracellularly, gradually suppressed IBa in a concentration-dependent manner. |
2(0,0,0,2) | Details |
| 1726794 | Lang RJ, Paul RJ: Effects of monoxime on whole-cell Ca2+ channel currents in single cells of the guinea-pig taenia caeci. J Physiol. 1991 Feb;433:1-24. Calcium channel currents were isolated using pipette solutions containing Cs+, tetraethylammonium and ATP (3 mM). Ca2+ channel currents in 7.5 mM-Ba2+ (IBa) were recorded at potentials positive to -40 mV, were maximal near 0 mV and reversed near +60 mV. |
2(0,0,0,2) | Details |
| 2457091 | Ganitkevich VYa, Shuba MF, Smirnov SV: Saturation of channels in single isolated smooth muscle cells of guinea-pig taenia caeci. J Physiol. 1988 May;399:419-36. Calcium channel currents were recorded in Cs+-dialysed voltage-clamped single smooth muscle cells isolated from the guinea-pig taenia caeci to evaluate the current-carrying ability of Ca2+, Ba2+, Sr2+ and Mg2+ ions. 2. Concentration dependences of (ICa), barium (IBa) and (ISr) currents were studied. |
2(0,0,0,2) | Details |
| 8662289 | Xu WX, Kim SJ, Kim SJ, So I, Kang TM, Rhee JC, Kim KW: Effect of stretch on calcium channel currents recorded from the antral circular myocytes of guinea-pig stomach. Pflugers Arch. 1996 Jun;432(2):159-64. The effect of membrane stretch on voltage-activated Ba2+ current (IBa) was studied in antral circular myocytes of guinea-pig using the whole- cell patch-clamp technique. |
2(0,0,0,2) | Details |
| 8528575 | Nagano N, Imaizumi Y, Watanabe M: Modulation of calcium channel currents by in single smooth muscle cells from vas deferens of the guinea-pig. Br J Pharmacol. 1995 Sep;116(2):1887-93. When Ca2+ or Ba2+ was the charge carrier, Ca channel current (ICa or IBa) was reduced by AA to a similar extent (IC50 = 10 and 6 microM, respectively). |
1(0,0,0,1) | Details |
| 2159060 | Doerner D, Abdel-Latif M, Rogers TB, Alger BE: Protein kinase C-dependent and -independent effects of phorbol esters on hippocampal calcium channel current. J Neurosci. 1990 May;10(5):1699-706. While both phorbol esters depressed whole-cell barium current through Ca channels (IBa), PDBu was approximately 100-fold more potent than 4 alpha-PDBu. |
1(0,0,0,1) | Details |
| 9313936 | Hernandez-Guijo JM, Gandia L, de Pascual R, Garcia AG: Differential effects of the neuroprotectant lubeluzole on bovine and mouse chromaffin cell calcium channel subtypes. Br J Pharmacol. 1997 Sep;122(2):275-85. The effects of lubeluzole (a neuroprotective benzothiazole derivative) and its (-) enantiomer R91154 on whole-cell currents through Ca2+ channels, with 10 mM Ba2+ as charge carrier (IBa), have been studied in bovine and mouse voltage-clamped chromaffin cells. |
1(0,0,0,1) | Details |
| 9878884 | Potier B, Rovira C: Protein tyrosine kinase inhibitors reduce high-voltage activating currents in CA1 pyramidal neurones from rat hippocampal slices. Brain Res. 1999 Jan 23;816(2):587-97. (100 microM) and tyrphostin B42 (100 microM), two PTKs inhibitors, reduced the steady-state barium current (IBa). In order to characterize the channels subtypes inhibited by PTKs inhibitors, we examined the effect of in the presence of different calcium channel blockers. |
1(0,0,0,1) | Details |
| 8865066 | Albillos A, Gandia L, Michelena P, Gilabert JA, del Valle M, Carbone E, Garcia AG: The mechanism of calcium channel facilitation in bovine chromaffin cells. J Physiol. 1996 Aug 1;494 ( Pt 3):687-95. A 1:1000 dilution of SVL in the external solution halved the magnitude of IBa and produced a 7-fold slowing of its activation kinetics. |
1(0,0,0,1) | Details |
| 2163275 | Scott RH, Dolphin AC: Voltage-dependent modulation of rat sensory neurone calcium channel currents by G protein activation: effect of a dihydropyridine antagonist. Br J Pharmacol. 1990 Apr;99(4):629-30. The ability of a depolarizing prepulse to increase the rate of activation of IBa has been examined in cultured sensory neurones of the rat. |
1(0,0,0,1) | Details |
| 1335820 | Doerner D, Alger BE: Evidence for hippocampal calcium channel regulation by PKC based on comparison of diacylglycerols and phorbol esters. Brain Res. 1992 Nov 27;597(1):30-40. We found that, like PDBu, the diacylglycerols (DAGs) suppressed whole-cell Ba2+ current (IBa) in a dose-dependent and reversible manner and caused a hyperpolarizing shift in the voltage dependence of steady-state IBa inactivation. |
1(0,0,0,1) | Details |
| 20201898 | Movafagh S, Morad M: L-type calcium channel as a cardiac sensor. Ann N Y Acad Sci. 2010 Feb;1188:153-8. The suppressive effect of anoxia was relieved by PKA-mediated phosphorylation only when Ca2+ was the charge carrier, whereas phosphorylated IBa remained sensitive to O2 withdrawal. |
1(0,0,0,1) | Details |