| Name | cholinesterases |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | chlorfenvinphos |
|---|---|
| CAS | 2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl phosphate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6774405 | Podolak M, Warchocki B: [Effect of toxobidine on the kinetics of cholinesterase inhibition reaction by chlorfenvinphos and carbaryl] Rocz Panstw Zakl Hig. 1980;31(2):25-31. |
81(1,1,1,1) | Details |
| 9478093 | Podolak M, Panasiuk L: Biological indicators for the assessment of human exposure to organophosphorous compounds. Przegl Lek. 1997;54(10):719-22. Cholinesterase activity in plasma and red blood cells was determined spectrophotometrically by the Ellman modified method. |
4(0,0,0,4) | Details |
| 11109745 | Lutz P, Tomas T, Gralewicz S, Nowakowska E: Long-term effects of acute exposure to chlorphenvinphos on behavioural responsiveness to amphetamine and in rats. Int J Occup Med Environ Health. 2000;13(3):215-22. We investigated the effect of acute exposure to chlorphenvinphos (CVP) (2-chloro-1 (2,4-dichlorophenyl)-vinyl-diethyl- an organophosphate anticholinesterase, on the amphetamine- and -induced open-field locomotion in Wistar rats. |
3(0,0,0,3) | Details |
| 15906004 | Halamek J, Pribyl J, Makower A, Skladal P, Scheller FW: Sensitive detection of organophosphates in river water by means of a piezoelectric biosensor. Anal Bioanal Chem. 2005 Aug;382(8):1904-11. Epub 2005 May 20. The total measurement time (binding+regeneration) was 25 min and the detection limit for different OP (paraoxon, diisopropylfluorophosphate, chlorpyriphos, and chlorfenvinphos) was down to 10 (-10) mol L (-1) (0.02 microg L (-1)). A highly sensitive piezoelectric biosensor has been developed for detection of cholinesterase inhibitors. |
3(0,0,0,3) | Details |
| 2132936 | Gralewicz S, Kowalczyk W, Gorny R, Socko R: Brain electrical activity (EEG) after repetitive exposure to chlorphenvinphos an organophosphate anticholinesterase: I. Pol J Occup Med. 1990;3(1):51-67. |
2(0,0,0,2) | Details |
| 2489432 | Socko R, Gralewicz S, Gorny R: Neurotoxicity of chlorphenvinphos an organophosphorus pesticide: effects on blood and brain cholinesterase activity, open field behavior and response-to-change in a "T" maze in rats. Pol J Occup Med. 1989;2(3):294-308. |
2(0,0,0,2) | Details |
| 12191930 | Collier WA, Clear M, Hart AL: Convenient and rapid detection of pesticides in extracts of sheep wool. Biosens Bioelectron. 2002 Sep;17(9):815-9. A relatively simple, rapid extraction technique based on acetonitrile was combined with the use of screen-printed electrodes bearing cholinesterases to detect organo- pesticides from an otherwise intractable matrix, sheep wool. |
2(0,0,0,2) | Details |
| 1392653 | Tomas T, Gralewicz S: A comparison of changes in spontaneous (EEG) and evoked brain activity induced by chlorphenvinphos and physostigmine in rats and rabbits. Pol J Occup Med Environ Health. 1992;5(1):55-69. The effects of single i.p. injections of two cholinesterase inhibitors, chlorphenvinphos (CVP) and physostigmine, on hippocampal and cortical EEG and flash evoked potentials in occipital cortex were compared in rabbits and rats. |
2(0,0,0,2) | Details |
| 2453047 | Pawlowska D, Kocmierska-Grodzka D, Moniuszko-Jakoniuk J: The effect of methylbromophenvinfos (Polfos) on some enzymes in vivo and in vitro. Pol J Pharmacol Pharm. 1987 Jul-Aug;39(4):361-70. The activities of cholinesterase (ChE), beta-glucuronidase (beta- lipase and amylase were assayed in the blood serum, the activity of acetylcholinesterase (AChE)-in brain homogenates, and the activities of lipase and amylase-in homogenates of the pancreas. |
2(0,0,0,2) | Details |
| 1799644 | Gralewicz S, Tomas T, Gorny R, Kowalczyk W, Socko R: Changes in brain bioelectrical activity (EEG) after repetitive exposure to an organo- anticholinesterase. Pol J Occup Med Environ Health. 1991;4(2):183-96. |
2(0,0,0,2) | Details |
| 2130875 | Gralewicz S, Socko R: Effects of a single exposure to chlorphenvinphos, an organophosphate insecticide, on hot-plate behaviour in rats. Pol J Occup Med. 1990;3(2):215-20. The test was repeated twice on the 18th and 19th days after the exposure, i.e. after a time sufficient for a full recovery of cholinesterase activity in the blood and brain. |
2(0,0,0,2) | Details |
| 2489433 | Gralewicz S, Tomas T, Socko R: Effects of single exposure to chlorphenvinphos, an organophosphate insecticide, on electrical activity (EEG) of the rat brain. Pol J Occup Med. 1989;2(3):309-20. The effect of a single exposure to an agricultural insecticide, chlorphenvinphos (CVP), an organophosphorus anticholinesterase, on neocortical seizure activity induced or promoted by cardiazol, and on hippocampal and neocortical EEG was studied in rats. |
2(0,0,0,2) | Details |
| 11218047 | Dekundy A, Blaszczak P, Kaminski R, Turski WA: On the interactions between antimuscarinic atropine and NMDA receptor antagonists in anticholinesterase-treated mice. Arch Toxicol. 2001 Jan;74(11):702-8. Adult Swiss mice were systemically injected with the OP pesticide, chlorfenvinphos (CVP), or the pesticide, methomyl (MET). |
1(0,0,0,1) | Details |
| 1855619 | Takahashi H, Kojima T, Ikeda T, Tsuda S, Shirasu Y: Differences in the mode of lethality produced through intravenous and oral administration of organophosphorus insecticides in rats. Fundam Appl Toxicol. 1991 Apr;16(3):459-68. This study was undertaken to investigate the possibility that mechanisms other than cholinesterase (ChE) inhibition account for the acute toxicity of organophosphorus insecticide. Both the P = O type insecticide (direct ChE inhibitors: chlorfenvinphos and dichlorvos) and the P = S type insecticide (indirect ChE inhibitors: diazinon and fenthion) were employed. |
1(0,0,0,1) | Details |
| 17826976 | Istamboulie G, Andreescu S, Marty JL, Noguer T: Highly sensitive detection of organophosphorus insecticides using magnetic microbeads and genetically engineered acetylcholinesterase. Biosens Bioelectron. 2007 Nov 30;23(4):506-12. Epub 2007 Aug 2. The developed sensor has been compared with those based on the widely used Electric eel cholinesterase and a classical entrapment procedure in a polyvinylalcohol-based matrix. The oriented and site-specific immobilisation combined with the high specificity of the B349 mutant allows a more sensitive detection of insecticides, concentrations as low as 1.31 (-11) M (IC10) being detected for both pesticides chlorpyriphos-oxon and chlorfenvinphos. |
1(0,0,0,1) | Details |
| 15019250 | Rickwood CJ, Galloway TS: Acetylcholinesterase inhibition as a biomarker of adverse effect. Aquat Toxicol. 2004 Mar 30;67(1):45-56. A study of Mytilus edulis exposed to the priority pollutant chlorfenvinphos.. However, scientific uncertainty about the risk assessment implications of data describing inhibition of cholinesterases in diverse species and tissues has hampered the use of AChE activity as a biomarker of adverse effect. |
1(0,0,0,1) | Details |
| 10465900 | Socko R, Gralewicz S, Gorny R: Long-term behavioural effects of a repeated exposure to chlorphenvinphos in rats. Int J Occup Med Environ Health. 1999;12(2):105-17. In a part of the rats, cholinesterase (ChE) activity in blood (plasma and erythrocytes), and in the selected brain regions was determined at arbitrarily chosen time after the last exposure. |
1(0,0,0,1) | Details |
| 7623739 | Gralewicz S, Tomas T, Socko R: Interaction of chlorphenvinphos with cholinergic receptors in the rabbit hypothalamus. Neurotoxicol Teratol. 1995 May-Jun;17(3):289-95. To attain this goal, the effects of intrahypothalamic injections of oxotremorine (Ox), a muscarinic agonist, and physostigmine (Phys), a anticholinesterase, were compared with those produced by intrahypothalamic injections of CVP in the rabbit. |
1(0,0,0,1) | Details |
| 2489411 | Gralewicz S, Tomas T, Gorny R, Kowalczyk W, Socko R: Changes in physiological and electrophysiological parameters in rabbits after single exposure to chlorphenvinphos. Pol J Occup Med. 1989;2(1):3-14. In order to evaluate some of the central effects of an organophosphorus pesticide--chlorphenvinphos (CVP), the time course of changes in the activity of blood cholinesterase (ChE), body temperature and hippocampal EEG were compared in rabbits after acute i.p. exposure. |
1(0,0,0,1) | Details |
| 1697627 | Yoshikawa H, Yoshida M, Hara I: Electroretinographic changes induced by organophosphorus pesticides in rats. J Toxicol Sci. 1990 May;15(2):87-95. Male Wistar rats were intraperitoneally injected with fenthion, chlorpyrifos, fenitrothion, dichlorvos or chlorfenvinphos at doses of 0.01 mmol/kg and/or 0.05 mmol/kg. The electroretinogram (ERG) was recorded at 5 hours and 2 days after the administration, and brain and retinochoroid cholinesterase (ChE) activities was assayed at 3 days after the injections. |
1(0,0,0,1) | Details |
| 6890179 | Maxwell IC, Le Quesne PM: Neuromuscular effects of chronic administration of two organophosphorus insecticides to rats. Neurotoxicology. 1982 Jul;3(1):1-10. Groups of rats were fed chlorfenvinphos (at two dose levels) or dicrotophos. Whole blood and plasma cholinesterase activity was markedly reduced. |
1(0,0,0,1) | Details |
| 985225 | Stone BF, Wilson JT, Youlton NJ: Linkage and dominance characteristics of genes for resistance to organophosphorus acaricides and allelic inheritance of decreased brain cholinesterase activity in three strains of the cattle tick, Boophilus microplus. Aust J Biol Sci. 1976 Jul;29(3):251-63. No F1 larval progeny from the following crossings were appreciably more resistant than their parents to these chemicals: R x B--bromophos ethyl and fenthion; B x M--carbaryl, chlorfenvinphos, chlorpyrifos, diazinon, dimethoate, ethion, fenthion and formothion; M x R--chlorfenvinphos, diazinon, dimethoate, ethion, formothion. |
1(0,0,0,1) | Details |
| 10909176 | Gralewicz S, Lutz P, Szymczak W: Hyposensitivity to amphetamine following exposure to chlorphenvinphos--protection by amphetamine preexposure. Acta Neurobiol Exp. 2000;60(2):203-8. We investigated the effect of an acute exposure to chlorphenvinphos (CVP), an organophosphate anticholinesterase, on amphetamine-induced open-field locomotion in rats. |
1(0,0,0,1) | Details |
| 1765223 | Ikeda T, Tsuda S, Shirasu Y: Metabolic induction of the hepatic cytochrome P450 system by chlorfenvinphos in rats. Fundam Appl Toxicol. 1991 Aug;17(2):361-7. This protection may be due to the reduction in brain cholinesterase inhibition caused by the decrease in plasma CVP concentration. |
1(0,0,0,1) | Details |
| 7153825 | Jay WM, Marcus RW, Jay MS: Primary position upbeat nystagmus with organophosphate poisoning. J Pediatr Ophthalmol Strabismus. 1982 Nov-Dec;19(6):318-9. A 21-month-old white girl swallowed Dermaton, an organophosphate pesticide, and developed primary position upbeat nystagmus, RBC and plasma cholinesterase levels were markedly depressed, confirming organophosphate poisoning. |
1(0,0,0,1) | Details |
| 2340983 | Ikeda T, Kojima T, Yoshida M, Takahashi H, Tsuda S, Shirasu Y: Pretreatment of rats with an organophosphorus insecticide, chlorfenvinphos, protects against subsequent challenge with the same compound. Fundam Appl Toxicol. 1990 Apr;14(3):560-7. Twenty-four hours after oral administration of CVP (15 mg/kg), the second dose (CVP 30 mg/kg, po) was less effective in inhibiting cholinesterase activities of the brain, erythrocyte, and plasma compared with naive rats treated with the same dose. |
1(0,0,0,1) | Details |
| 10384211 | Konieczny B, Kossmann S, Makuch M: Impaired respiratory muscle function in chemical plant workers producing chlorfenvinphos. Ann Agric Environ Med. 1999;6(1):21-5. |
0(0,0,0,0) | Details |