| 6873616 |
Rex D, Lumeng L, Eble J, Rex L: Intrahepatic cholestasis and sicca complex after thiabendazole. Gastroenterology. 1983 Sep;85(3):718-21.
Report of a case and review of the literature.. Thiabendazole is a relatively safe and effective agent with a wide range of activity against nematodes infesting the gastrointestinal tract. A 55-yr-old man developed prolonged jaundice and sicca complex after a course of thiabendazole therapy. Endoscopic retrograde cholangiopancreatography demonstrated normal biliary tree and pancreatic ducts. Liver biopsy was consistent with a drug-induced intrahepatic cholestatic reaction. The patient recovered completely from his liver injury, but the sicca complex persisted 1 yr after the drug was given. The literature on thiabendazole-induced cholestasis and its association with sicca complex is reviewed. |
6(0,0,1,1) |