Protein Information

ID 130
Name serum cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

ID 222
Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference

PubMed Abstract RScore(About this table)
3415898 Perez Guillermo F, Martinez Pretel CM, Tarin Royo F, Pena Macias MJ, Alvarez Ossorio R, Alvarez Gomez JA, Vidal CJ: Prolonged suxamethonium-induced neuromuscular blockade associated with organophosphate poisoning. Br J Anaesth. 1988 Aug;61(2):233-6.
We report a patient, exposed to Malathion during agricultural work, who suffered a prolonged apnoea after the administration of suxamethonium. He had a normal phenotype (E1u E1u), but an extremely low plasma cholinesterase activity. The diagnosis was made by assaying cholinesterase activity and analysing the enzymic components by electrophoresis on polyacrylamide gel slabs. The results indicated that the apnoea was a result of the low activity of plasma cholinesterase induced by Malathion.
8(0,0,1,3)