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profenofos

Identification (Source:EPA,EU)

ID	1556
Name	profenofos
CAS	41198-08-7
IUPAC
Inchi	InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3
CIPAC	461
EPA Code	111401
Formula	C11H15BrClO3PS
SMILES	CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl
Status	Not Approved

Classification

Mode of Action	Non-systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type	Insecticide, Acaricide
Chemical Group	Organophosphate
Classification	phenyl organothiophosphate insecticides organothiophosphate insecticides

Properties (Source:PubChem)

Molecular Weight	373.63
Physical State	Pale yellow liquid
AlogP	4.79
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	307.81
Polar Surface Area	70.64

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Aquatic crustaceans	Acute	96 hour	LC50	0.0016 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.5 mg l-1
Birds	Acute		LD50	70 mg kg-1
Fish	Acute	96 hour	LC50	0.08 mg l-1
Honeybees	Acute	48 hour	LD50	0.095 μg bee-1
Mammals	Acute oral		LD50	358 mg kg-1
Mammals	Short term dietary		NOEL	0.3 ppm diet
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	1186

Related targets

Target Name	RScore (About this table)
Acetylcholinesterase	1266(12,19,23,76)	Details
cholinesterase	146(1,2,5,21)	Details
Fatty acid amide hydrolase	39(0,1,1,9)	Details
CYP3A4	33(0,1,1,3)	Details
CYP2D6	33(0,1,1,3)	Details
CYP2C9	32(0,1,1,2)	Details
CYP1A1	32(0,1,1,2)	Details
CYP2B6	31(0,1,1,1)	Details
CYP2C8	31(0,1,1,1)	Details
cytochrome P450 (protein family or complex)	20(0,0,2,10)	Details

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