Protein Information

Name P13
Synonyms 3' 5' exoribonuclease CSL4 homolog; 3' 5' exoribonuclease CSL4 homolog; CGI 108; CGI108; CSL 4; CSL4; Csl4p; EXOSC 1…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
10627581 Iwasaki S, Momiyama A, Uchitel OD, Takahashi T: Developmental changes in calcium channel types mediating central synaptic transmission. J Neurosci. 2000 Jan 1;20(1):59-65.


In fact, Ca (2+) currents directly recorded from the auditory calyceal presynaptic terminal were identified as N-, P/Q-, and R-types at postnatal day 7 (P7) to P10 but became predominantly P/Q-type at P13.
1(0,0,0,1) Details
11067975 Nunez-Abades PA, Pattillo JM, Hodgson TM, Cameron WE: Role of synaptic inputs in determining input resistance of developing brain stem motoneurons. J Neurophysiol. 2000 Nov;84(5):2317-29.

Comparing across age groups, there was a significantly larger percent change in R (n) with the addition of high Mg (2+) at postnatal days 13 to 15 (P13-15; 36%) than that found at P5-6 (21%).
Spontaneous postsynaptic potentials were sensitive to the combined application of glycine receptor antagonist, strychnine, and the GABA (A) receptor antagonist, bicuculline.
1(0,0,0,1) Details
9851655 Rodriguez-Ithurralde D, Maruri A, Rodriguez X: Motor neurone acetylcholinesterase release precedes neurotoxicity caused by systemic administration of excitatory amino acids and strychnine. J Neurol Sci. 1998 Oct;160 Suppl 1:S80-6.

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18234240 Pedroarena CM, Kamphausen S: Glycinergic synaptic currents in the deep cerebellar nuclei. . Neuropharmacology. 2008 Apr;54(5):784-95. Epub 2007 Dec 23.


Spontaneous glycinergic IPSCs were very rare but direct presynaptic depolarization by superfusion with elevated potassium concentration or application of 4-aminopyridine consistently evoked strychnine sensitive IPSCs.
0(0,0,0,0) Details