| Name | mu opioid receptors |
|---|---|
| Synonyms | MOR 1; MOR1; Mu opiate receptor; Mu opioid receptor; Mu type opioid receptor; OPRM; OPRM 1; OPRM1… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9121816 | Sorkin LS, Puig S: Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a mu-opiate receptor agonist. Pain. 1996 Dec;68(2-3):283-92. |
81(1,1,1,1) | Details |
| 7952857 | Hunter JC, Atwal P, Woodruff GN, Singh L: Differential modulation of kappa and mu opioid antinociception by the /NMDA receptor agonist Br J Pharmacol. 1994 Aug;112(4):1002-3. a selective agonist for the strychnine-insensitive allosteric site associated with the NMDA receptor-ion channel complex, was found to modulate differentially the antinociception produced by kappa and mu-opioid receptor agonists in the rat formalin test. |
31(0,1,1,1) | Details |
| 12356896 | Johnson SM, Wilkerson JE, Wenninger MR, Henderson DR, Mitchell GS: Role of synaptic inhibition in turtle respiratory rhythm generation. J Physiol. 2002 Oct 1;544(Pt 1):253-65. The bicuculline-strychnine rhythm frequency decreased during mu-opioid receptor activation or decreased bath P (C)(O (2)). |
31(0,1,1,1) | Details |
| 8046463 | Glaum SR, Miller RJ, Hammond DL: Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord. J Neurosci. 1994 Aug;14(8):4965-71. Excitatory postsynaptic currents (EPSCs) or potentials (EPSPs) were evoked electrically at the ipsilateral dorsal root entry zone after blocking inhibitory inputs with bicuculline and strychnine, and NMDA receptors with D-2-amino-5-phosphonopentanoic acid. |
2(0,0,0,2) | Details |
| 11728420 | Jeong HJ, Lee JJ, Hahm ET, Han SH, Min BI, Cho YW: Role of protein kinase C in opioid modulation of -gated Cl (-) current in rat periaqueductal gray neuron. Eur J Pharmacol. 2001 Nov 16;431(2):143-50. The Role of protein kinase C in the modulatory effect of a mu-opioid receptor agonist, [D- (2),N-Me- (4),Gly (5)-ol] enkephalin (DAMGO), on the -gated Cl (-) current was examined in acutely dissociated rat periaqueductal gray neurons. The -gated Cl (-) current (I (Gly)) was sensitive to strychnine. |
2(0,0,0,2) | Details |
| 7858868 | Neal MJ, Paterson SJ, Cunningham JR: Enhancement of retinal release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect. Br J Pharmacol. 1994 Nov;113(3):789-94. The mu-opioid receptor agonist, [D-Ala2, MePhe4, Gly-ol5]-enkephalin (DAMGO), when applied locally to the retina at concentrations between 1-30 microM significantly increased the light-evoked release of Blockade with bicuculline and strychnine of GABAergic and glycinergic inputs to the cholinergic neurones did not affect the action of DAMGO on release. |
2(0,0,0,2) | Details |
| 11160487 | Terman GW, Eastman CL, Chavkin C: Mu opiates inhibit long-term potentiation induction in the spinal cord slice. J Neurophysiol. 2001 Feb;85(2):485-94. Transverse slices were made from the lumbar spinal cord of 10- to 17-day-old rats, placed in a recording chamber, and perfused with artificial cerebrospinal fluid also containing bicuculline (10 microM) and strychnine (1 microM). Only LT-evoked field potentials were found to be reliably inhibited by the mu opioid receptor agonist [D- (2), N-Me- (4), Gly (5)] enkephalin-ol (DAMGO, 1 microM), although evoked potentials from both DR and LT were blocked by the AMPA/kainate glutamate receptor antagonist 6-cyano-7-nitroquinoxalene-2,3-dione. |
1(0,0,0,1) | Details |
| 9622453 | Darstein M, Albrecht C, Lopez-Francos L, Knorle R, Holter SM, Spanagel R, Feuerstein TJ: Release and accumulation of neurotransmitters in the rat brain: acute effects of in vitro and effects of long-term voluntary intake. Alcohol Clin Exp Res. 1998 May;22(3):704-9. Slices of the rat caudatoputamen were prelabeled with [3H] and release of [3H] was stimulated through either (NMDA) receptors or strychnine-sensitive glycine receptors. Electrically evoked release of [3H] ([3H] NA) and its presynaptic modulation by morphine through mu-opioid receptors in neocortical slices of the rat, preloaded with [3H] NA, was nearly identical in both -naive rats and in drinking rats. |
1(0,0,0,1) | Details |
| 9772256 | Hayar A, Guyenet PG: Pre- and postsynaptic inhibitory actions of methionine-enkephalin on identified bulbospinal neurons of the rat RVL. J Neurophysiol. 1998 Oct;80(4):2003-14. The inhibitory effects of ME were mimicked by the selective mu-opioid receptor agonist (EM, 3 microM) and were blocked by naloxone (1 microM). The remaining mPSCs had much slower kinetics (decay time = 19.6 ms) and were GABAergic [miniature inhibitory postsynaptic currents (mIPSCs)] as they were blocked by gabazine (3 microM) but not by strychnine (3-10 microM). |
1(0,0,0,1) | Details |