| Name | complex is |
|---|---|
| Synonyms | 39kD; CI 39kD; Complex I; Complex I 39kD; NADH dehydrogenase (ubiquinone) Fe S protein 2 like; NADH ubiquinone oxidoreductase 39 kDa subunit mitochondrial; NADH ubiquinone oxidoreductase 39 kDa subunit; NDUFA 9… |
| Name | thiabendazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15280226 | Tange Y, Fujita A, Toda T, Niwa O: Functional dissection of the gamma-tubulin complex by suppressor analysis of gtb1 and alp4 mutations in Schizosaccharomyces pombe. Genetics. 2004 Jul;167(3):1095-107. These results suggested that the function of the gamma-tubulin complex or the requirement of each component of the complex is differentially regulated between the vegetative and sexual phases of the life cycle in fission yeast. The cold sensitivity of gamma-tubulin mutants was almost completely suppressed by an alpha-tubulin mutation and partially suppressed by a low concentration of thiabendazole, a microtubule assembly inhibitor. |
1(0,0,0,1) | Details |
| 16079915 | Sanchez-Perez I, Renwick SJ, Crawley K, Karig I, Buck V, Meadows JC, Franco-Sanchez A, Fleig U, Toda T, Millar JB: The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast. EMBO J. 2005 Aug 17;24(16):2931-43. Epub 2005 Aug 4. We identified a truncated allele of dam1 as a multicopy suppressor of the sensitivity of cdc13-117 (cyclin B) and mal3-1 (EB-1) cells to thiabendazole, a microtubule poison. We find that the mitotic centromere-associated Klp5/Klp6 kinesin complex is essential in cells lacking components of the DASH complex. |
1(0,0,0,1) | Details |
| 7622334 | Armson A, Grubb WB, Mendis AH: The effect of electron transport (ET) inhibitors and thiabendazole on the reductase (FR) and succinate dehydrogenase (SDH) of Strongyloides ratti infective (L3) larvae. Int J Parasitol. 1995 Feb;25(2):261-3. This strongly suggests that the S. ratti FR is functionally linked with the S. ratti ET-Complex I. 2-Thenoyltrifluoroacetone (TTFA, an inhibitor of ET-Complex II) inhibited FR (EC50 = 2.6 x 10 (-5) M) and SDH (EC50 = 2.8 x 10 (-5) M) with similar effectiveness. |
1(0,0,0,1) | Details |
| 6873616 | Rex D, Lumeng L, Eble J, Rex L: Intrahepatic cholestasis and sicca complex after thiabendazole. Gastroenterology. 1983 Sep;85(3):718-21. The literature on thiabendazole-induced cholestasis and its association with sicca complex is reviewed. |
6(0,0,1,1) | Details |
| 14607231 | Mothilal KK, Karunakaran C, Sambasiva Rao P, Murugesan R: Single crystal EPR of Cu (II) doped [Co (tbz) 2 (NO3)(H2O)] NO3: probe into -thiabendazole interaction. Spectrochim Acta A Mol Biomol Spectrosc. 2003 Dec;59(14):3337-45. The low magnitude of A33 of the complex is rationalized in terms of admixture of d (x2-y2)/d (z2) ground state and delocalization of unpaired spin density onto the ligands. |
1(0,0,0,1) | Details |