Protein Information

Name HEMA
Synonyms AHF; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII precursor; DXS1253E; F8; F8 protein; F8B…

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
15491483 Maldonado-Codina C, Efron N: Impact of manufacturing technology and material composition on the mechanical properties of hydrogel contact lenses. Ophthalmic Physiol Opt. 2004 Nov;24(6):551-61.


The five lens groups consisted of three polyhydroxyethyl methacrylate (pHEMA) lenses which were each manufactured by a different technique: lathing, spin-casting and cast-moulding, a HEMA/methacrylic acid (HEMA/MAA) cast-moulded lens and a HEMA/glycerol methacrylate (HEMA/GMA) cast-moulded lens.
2(0,0,0,2) Details
15023451 He H, Cao X, Lee LJ: Design of a novel hydrogel-based intelligent system for controlled drug release. J Control Release. 2004 Mar 24;95(3):391-402.


In this device, a pH-sensitive hydrogel together with a poly (hydroxyethyl methacrylate) (HEMA) barrier was used as a gate to control drug release.
2(0,0,0,2) Details
14615176 Hiratani H, Alvarez-Lorenzo C: The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems. Biomaterials. 2004 Mar;25(6):1105-13.


Four types of timolol imprinted lenses were prepared by UV irradiation of N,N-diethylacrylamide (DEAA), 2-hydroxyethylmethacrylate (HEMA), 1-(tristrimethyl-siloxysilylpropyl)-methacrylate (SiMA) and N,N-dimethylacrylamide (DMAA) (50:50 v/v), or methylmethacrylate (MMA) and DMAA (50:50 v/v) solutions, to which functional monomer, methacrylic acid (MAA, 100 mM), cross-linker, ethyleneglycol dimethacrylate (EGDMA, 140 mM), and timolol maleate (25 mM) were previously added.
2(0,0,0,2) Details
18600641 Kondo A, Oku S, Higashitani K: Adsorption of gamma-globulin, a model protein for antibody, on colloidal particles. Biotechnol Bioeng. 1991 Mar 15;37(6):537-43.


Polystyrene latex (PS), hydrophilic copolymer lattices of styrene/2-hydroxyethyl methacrylate [P (S/HEMA)], styrene/ methacrylic acid [P (S/MAA)] and methyl methacrylate/ 2-hydroxyethyl methacrylate [P (MMA/HEMA)], and colloidal silica were used.
2(0,0,0,2) Details
3676418 van Wachem PB, Hogt AH, Beugeling T, Feijen J, Bantjes A, Detmers JP, van Aken WG: Adhesion of cultured human endothelial cells onto methacrylate polymers with varying surface wettability and charge. Biomaterials. 1987 Sep;8(5):323-8.


HEC adhesion in CMS onto (co) polymers of hydroxyethyl methacrylate (HEMA) and methyl methacrylate (MMA) was found to be optimal on the moderately wettable copolymer (mol ratio 25 HEMA/75 MMA).
2(0,0,0,2) Details
16303542 Tranoudis I, Efron N: Water properties of soft contact lens materials. Cont Lens Anterior Eye. 2004 Dec;27(4):193-208.


Specifically, lenses made from the following eight materials (and nominal water contents) were used: HEMA/VP 40%, HEMA/VP 55%, HEMA/VP 70%, VP/MMA 55%, VP/MMA 70%, HEMA 40%, HEMA/MAA 55% and HEMA/MAA 70% [HEMA = 2-hydroxy-ethyl methacrylate, VP = vinyl pyrrolidone, MMA = methyl methacrylate, MAA = methacrylic acid].
1(0,0,0,1) Details
16303536 Tranoudis I, Efron N: In-eye performance of soft contact lenses made from different materials. Cont Lens Anterior Eye. 2004 Sep;27(3):133-48.


This study describes clinical and laboratory experiments that were conducted in order to examine the in-eye performance of eight soft contact lenses manufactured from different materials; these materials (and nominal water contents) were: HEMA/VP 40%, HEMA/VP 55%, HEMA/VP 70%, VP/MMA 55%, VP/MMA 70%, HEMA 40%, HEMA/MAA 55% and HEMA/MAA 70% (HEMA: 2-hydroxy-ethyl methacrylate, VP: vinyl pyrrolidone, MMA: methyl methacrylate, MAA: methacrylic acid).
1(0,0,0,1) Details
18727860 Suhag GS, Bhatnagar A, Singh H: Poly (hydroxyethyl methacrylate)-based co-polymeric hydrogels for transdermal delivery of salbutamol sulphate. J Biomater Sci Polym Ed. 2008;19(9):1189-200.


Various co-polymeric hydrogels for transdermal delivery of salbutamol sulphate were synthesized using 2-hydroxyethyl methacrylate (HEMA), methacrylic acid (MAA) and N-[3-(dimethylamino) propyl] methacrylamide (DMAPMA) in the presence of ammonium persulphate (APS) and N,N,N',N'-tetramethylethylenediamine (TEMED) as redox free radical initiator and ethyleneglycol dimethacrylate (EGDMA) as a cross-linker.
1(0,0,0,1) Details
15885992 Zhu JH, Zhang B, Fang WW, Lao XJ, Yu H: Characterization of amphoteric multilayered thin films by means of zeta potential measurements. Colloids Surf B Biointerfaces. 2005 Jun 10;43(1):1-6.


Multilayer films of amphoteric methylated collagen were assembled on SOURCE 15S or SOURCE 15Q beads by sequential electrostatic deposition with negatively charged methylacrylic acid-hydroxyethyl methacrylate-methyl methacrylate (MAA-HEMA-MMA) terpolymer.
1(0,0,0,1) Details
16835716 Mahkam M, Doostie L, Siadat SO: Synthesis and characterization of acrylic type hydrogels containing azo derivatives of 5-amino salicylic acid for colon-specific drug delivery. Inflammopharmacology. 2006 Mar;14(1-2):72-5.


Terephthalic acid was covalently linked with 2-hydroxyethyl methacrylate (HEMA), abbreviated as cross-linking agent (CA).
1(0,0,0,1) Details
2207229 Lopour P, Vondracek P, Janatova V, Sulc J, Vacik J: Silicone rubber-hydrogel composites as polymeric biomaterials. Biomaterials. 1990 Aug;11(6):397-402.


For composite materials containing a lightly cross-linked 2-hydroxyethylmethacrylate (HEMA)-methacrylic acid (MAA) copolymer and polymethacrylic acid (PMAA) as the hydrogel phase, permeability to water-soluble organic compounds and drugs were measured.
1(0,0,0,1) Details
15925718 Zhu JH, Wang XW, Ng S, Quek CH, Ho HT, Lao XJ, Yu H: Encapsulating live cells with water-soluble chitosan in physiological conditions. J Biotechnol. 2005 Jun 29;117(4):355-65.


The microcapsules consisted of an inner core of half N-acetylated chitosan and an outer shell of methacrylic acid (MAA) (20.4%)-hydroxyethyl methacrylate (HEMA) (27.4%)-methyl methacrylate (MMA) (52.2%) (MAA-HEMA-MMA) terpolymer.
1(0,0,0,1) Details
18954151 Lv H, Lin Q, Zhang K, Yu K, Yao T, Zhang X, Zhang J, Yang B: Facile fabrication of monodisperse polymer hollow spheres. Langmuir. 2008 Dec 2;24(23):13736-41.


In this method, P (St-MMA-MAA) copolymer latex particles were first prepared by emulsifier-free emulsion polymerization and then used as seeds to carry out emulsion polymerization of methyl methacrylate (MMA), divinyl benzene (DVB), and 2-hydroxyethyl methacrylate (HEMA) with potassium persulfate (KPS) as initiator at 80 degrees C.
1(0,0,0,1) Details
19582843 Park JG, Ye Q, Topp EM, Spencer P: Enzyme-catalyzed hydrolysis of dentin adhesives containing a new urethane-based trimethacrylate monomer. J Biomed Mater Res B Appl Biomater. 2009 Nov;91(2):562-71.

Dentin adhesives containing 2-hydroxyethyl methacrylate (HEMA, 45% w/w) and 2,2-bis [4 (2-hydroxy-3-methacryloyloxy-propyloxy)-phenyl] propane (BisGMA, 30% w/w) in addition to MPE (25% w/w) were formulated with H (2) O at 0 (MPE0), 8 (MPE8), and 16 wt % water (MPE16) to simulate the wet demineralized dentin matrix and compared with controls [HEMA /BisGMA, 45/55 w/w, at 0 (C0), 8 (C8), and 16 wt % water (C16)].
On exposure to porcine liver esterase, the net cumulative methacrylic acid (MAA) released from the new adhesives was dramatically (p < 0.05) decreased relative to the control, suggesting that the new monomer improves esterase resistance.
1(0,0,0,1) Details
16233976 Perez-Moral N, Mayes AG: Direct rapid synthesis of MIP beads in SPE cartridges. Biosens Bioelectron. 2006 Mar 15;21(9):1798-803. Epub 2005 Oct 17.


In this initial study, 36 polymers were synthesised to study the effect of a variation in the type and amount of four different functional monomers, methacrylic acid (MAA), acrylic acid (AA), hydroxyethyl methacrylate (HEMA) and 2-vinylpyridine (2-VPy), for the imprinting of propranolol and morphine.
1(0,0,0,1) Details
20152401 Liu Y, Hoshina K, Haginaka J: Monodispersed, molecularly imprinted polymers for cinchonidine by precipitation polymerization. Talanta. 2010 Mar 15;80(5):1713-8. Epub 2009 Oct 14.


MIP1 was prepared using methacrylic acid (MAA) as a functional monomer and divinylbenzene (DVB) as a cross-linker and MIP2 was prepared with further addition of 2-hydroxyethyl methacrylate (HEMA) as a co-monomer.
1(0,0,0,1) Details
14653745 Dirion B, Cobb Z, Schillinger E, Andersson LI, Sellergren B: Water-compatible molecularly imprinted polymers obtained via high-throughput synthesis and experimental design. J Am Chem Soc. 2003 Dec 10;125(49):15101-9.


The variable factors were the added amount of the hydrophilic comonomer, 2-hydroxyethyl methacrylate (HEMA), the cross-linking ratio, and the porogen.
1(0,0,0,1) Details
15871691 Toh YC, Ng S, Khong YM, Samper V, Yu H: A configurable three-dimensional microenvironment in a microfluidic channel for primary hepatocyte culture. Assay Drug Dev Technol. 2005 Apr;3(2):169-76.


This is based on the laminar flow complex coacervation of a pair of oppositely charged polyelectrolytes, i.e., methylated collagen and a terpolymer of HEMA-MMA-MAA. 3D collagen matrices were formed with minimal gelation times (<8 min), were able to entrap cells under aqueous noncytotoxic conditions, and permitted culture media to be perfused in the microchannel by virtue of the spatial confinement of the 3D matrix on one side of the channel.
1(0,0,0,1) Details
4052547 Castillo EJ, Koenig JL, Anderson JM, Lo J: Protein adsorption on hydrogels. Biomaterials. 1985 Sep;6(5):338-45.


Lysozyme was adsorbed on spin cast and lathe cut soft contact lenses of poly-2-hydroxyethylmethacrylate (PHEMA) and on poly-HEMA-methacrylic acid (PHEMA/MAA).
1(0,0,0,1) Details
15020127 Quek CH, Li J, Sun T, Chan ML, Mao HQ, Gan LM, Leong KW, Yu H: Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation. Biomaterials. 2004 Aug;25(17):3531-40.


New anionic polyelectrolyte tetra-copolymers with photo-crosslinkable 4-(4-methoxycinnamoyl) phenyl methacrylate monomer in addition to a HEMA-MMA-MAA ter-copolymer system were synthesized.
1(0,0,0,1) Details
3700446 Hogt AH, Dankert J, Feijen J: Adhesion of coagulase-negative staphylococci to methacrylate polymers and copolymers. J Biomed Mater Res. 1986 Apr;20(4):533-45.


Decreasing rates of adhesion of CNS were observed onto MMA/HEMA copolymers with increasing HEMA content coinciding with increasing hydrophilicity.
1(0,0,0,1) Details
11774851 Chia SM, Wan AC, Quek CH, Mao HQ, Xu X, Shen L, Ng ML, Leong KW, Yu H: Multi-layered microcapsules for cell encapsulation. Biomaterials. 2002 Feb;23(3):849-56.


Type-1 microcapsules with an average diameter of 400 microm were formed by complexing modified collagen with a ter-polymer shell of 2-hydroxyethyl methylacrylate (HEMA), methacrylic acid (MAA) and methyl methacrylate (MMA), resulting in a capsule thickness of 2-5 microm.
1(0,0,0,1) Details
17121357 Zhu J, Zhang B, Yan X, Lao X, Yu H: [Encapsulating hepatocytes with chitosan in physiological conditions] . Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Oct;23(5):1070-4.

Prepared from 15.3% N-acetylated chitosan (FNC), half N-acetylated chitosan (HNC) possesses a good solubility in a weak basic solution, guaranteeing the formation of microcapsules by the coacervating reaction between HNC and methacrylic acid (MAA)-hydroxyethyl methacrylate (HEMA)-methyl methacrylate (MMA) (MAA-HEMA-MMA) terpolymer under physiological conditions.
31(0,1,1,1) Details
17228910 Brady C, Bell SE, Parsons C, Gorman SP, Jones DS, McCoy CP: Novel porphyrin-incorporated hydrogels for photoactive intraocular lens biomaterials. J Phys Chem B. 2007 Jan 25;111(3):527-34.


Novel surface-modified hydrogel materials have been prepared by binding charged porphyrins TMPyP (tetrakis (4-N-methylpyridyl) porphyrin) and TPPS (tetrakis (4-sulfonatophenyl) porphyrin) to copolymers of HEMA (2-hydroxyethyl methacrylate) with either MAA (methacrylic acid) or DEAEMA (2-(diethylamino) ethyl methacrylate).
1(0,0,0,1) Details
9851722 Monti P, Simoni R, Caramazza R, Bertoluzza A: Applications of Raman spectroscopy to ophthalmology: spectroscopic characterization of disposable soft contact lenses. Biospectroscopy. 1998;4(6):413-9.

Disposable soft contact lenses based on HEMA-MAA hydrogels are examined using Raman and ATR/FTIR vibrational spectroscopies and thermal analysis.
12(0,0,2,2) Details
20176462 Gao B, Hu H, Guo J, Li Y: Preparation of polymethacrylic acid-grafted HEMA/PVP microspheres and preliminary study on basic protein adsorption. Colloids Surf B Biointerfaces. 2010 Jun 1;77(2):206-13. Epub 2010 Feb 4.

9(0,0,0,9) Details
18395826 Kostoryz EL, Dharmala K, Ye Q, Wang Y, Huber J, Park JG, Snider G, Katz JL, Spencer P: Enzymatic biodegradation of HEMA/bisGMA adhesives formulated with different water content. J Biomed Mater Res B Appl Biomater. 2009 Feb;88(2):394-401.

6(0,0,0,6) Details
16303541 Tranoudis I, Efron N: Tensile properties of soft contact lens materials. Cont Lens Anterior Eye. 2004 Dec;27(4):177-91.


Lenses from the following eight materials (and nominal water contents) were used: HEMA/VP 40%, HEMA/VP 55%, HEMA/VP 70%, VP/MMA 55%, VP/MMA 70%, HEMA 40%, HEMA/MAA 55% and HEMA/MAA 70% (HEMA: 2-hydroxy-ethyl methacrylate, VP: vinyl pyrrolidone, MMA: methyl methacrylate, MAA: methacrylic acid).
4(0,0,0,4) Details
14568407 Uchida R, Sato T, Tanigawa H, Uno K: Azulene incorporation and release by hydrogel containing methacrylamide propyltrimenthylammonium chloride, and its application to soft contact lens. J Control Release. 2003 Oct 30;92(3):259-64.


The hydrogels contain cationic functional group in its side chain were prepared with 2-hydroxyethyl methacylate (HEMA) and methacrylamide propyltrimethylammonium chloride (MAPTAC).
1(0,0,0,1) Details
3741958 Deng XM, Castillo EJ, Anderson JM: Surface modification of soft contact lenses: silanization, wettability and lysozyme adsorption studies. Biomaterials. 1986 Jul;7(4):247-51.

The surface reactions of poly (2-hydroxyethylmethacrylate) (PHEMA) and the copolymer poly (HEMA-methacrylic acid) (PHEMA/MAA) with methyltrimethoxysilane, ethyltrimethoxysilane and phenyltrimethoxysilane have been characterized by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy.
6(0,0,1,1) Details
20001660 Tokumura F, Matsui T, Suzuki Y, Sado M, Taniguchi M, Kobayashi I, Kamiyama M, Suda S, Nakamura A, Yamazaki Y, Yamori A, Igarashi R, Kawai J, Oka K: The potential dermal irritating effect of residual (meth) acrylic monomers in pressure sensitive adhesive tapes. Drug Chem Toxicol. 2010;33(1):1-7.


We studied seven acrylic monomers, acrylic acid (AA), methyl acrylate (MA), ethyl acrylate (EA), n-butyl acrylate (n-BA), n-hexyl acrylate (n-HA), 2-ethylhexyl acrylate (2-EHA) and 2-hydroxyethyl acrylate (HEA), as well as three methacrylic monomers, methacrylic acid (MAA), methyl methacrylate (MMA) and 2-hydroxyethyl methacrylate (2-HEMA).
1(0,0,0,1) Details
1764557 Harkes G, Feijen J, Dankert J: Adhesion of Escherichia coli on to a series of poly (methacrylates) differing in charge and hydrophobicity. Biomaterials. 1991 Nov;12(9):853-60.


Polymers used were poly (methyl methacrylate) (PMMA), poly (hydroxyethyl methacrylate) (PHEMA) and copolymers of MMA or HEMA with either 15% methacrylic acid (MAA) or 15% trimethylaminoethyl methacrylate-HCl salt (TMAEMA-Cl).
1(0,0,0,1) Details
20141506 Mahkam M: Novel pH-sensitive hydrogels for colon-specific drug delivery. Drug Deliv. 2010 Apr;17(3):158-63.


Cubane-1,4-dicarboxylic acid (CDA), linked to two 2-hydroxyethyl methacrylate (HEMA) groups, was the cross-linking agent (CA).
1(0,0,0,1) Details
18359032 Wang X, Lu H, Lin X, Xie Z: Electrochromatographic characterization of methacrylate-based monolith with mixed mode of hydrophilic and weak electrostatic interactions by pressurized capillary electrochromatography. J Chromatogr A. 2008 May 9;1190(1-2):365-71. Epub 2008 Mar 7.


A monolithic stationary phase was prepared by in situ copolymerization of 2-hydroxyethyl methacrylate (HEMA), ethylene dimethacrylate (EDMA), and methacrylic acid (MAA), in a binary porogenic solvent consisting of toluene and 1-dodecanol.
1(0,0,0,1) Details
12226845 Alvarez-Lorenzo C, Hiratani H, Gomez-Amoza JL, Martinez-Pacheco R, Souto C, Concheiro A: Soft contact lenses capable of sustained delivery of timolol. . J Pharm Sci. 2002 Oct;91(10):2182-92.


The aim of this work was to evaluate the influence of the composition and the application of an imprinting technique on the loading capability of weakly crosslinked hydroxyethyl methacrylate (HEMA) hydrogels, with a view to their use as reloadable soft contact lenses for administration of timolol.
4(0,0,0,4) Details
11336291 De Groot CJ, Van Luyn MJ, Van Dijk-Wolthuis WN, Cadee JA, Plantinga JA, Den Otter W, Hennink WE: In vitro biocompatibility of biodegradable dextran-based hydrogels tested with human fibroblasts. Biomaterials. 2001 Jun;22(11):1197-203.


The cytotoxicity of dextran T40, methacrylated dextran (dex-MA) and hydroxyethyl-methacrylated dextran (dex-HEMA), dextran-based hydrogel discs and microspheres, and their degradation products, was studied by measuring the cell proliferation inhibition index (CPII) on human fibroblasts in vitro.
4(0,0,0,4) Details
8957708 Vakkalanka SK, Brazel CS, Peppas NA: Temperature- and pH-sensitive terpolymers for modulated delivery of streptokinase. J Biomater Sci Polym Ed. 1996;8(2):119-29.


Copolymer hydrogels composed of N-isopropylacrylamide (NIPAAm) and methacrylic acid (MAA) as well as terpolymer hydrogels containing NIPAAm, acrylic acid (AA), and 2-hydroxyethyl methacrylate (HEMA) were synthesized.
3(0,0,0,3) Details
16025474 Mahkam M: Using pH-sensitive hydrogels containing cubane as a crosslinking agent for oral delivery of insulin. J Biomed Mater Res B Appl Biomater. 2005 Oct;75(1):108-12.


Copolymers of 2-hydroxyethyl methacrylate (HEMA) and methacrylic acid (MAA) based hydrogels containing 2, 4, and 6% of a crosslinking agent (CA) were studied as drug delivery systems.
3(0,0,0,3) Details
10845587 Garrett Q, Laycock B, Garrett RW: Hydrogel lens monomer constituents modulate protein sorption. Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1687-95.


METHODS: A series of hydroxyethylmethacrylate (HEMA)-based hydrogels with various amounts of methacrylic acid (MAA) or N-vinyl pyrrolidone (NVP) were synthesized.
3(0,0,0,3) Details
16183113 Lord MS, Stenzel MH, Simmons A, Milthorpe BK: Lysozyme interaction with poly (HEMA)-based hydrogel. Biomaterials. 2006 Mar;27(8):1341-5. Epub 2005 Sep 23.

3(0,0,0,3) Details
15203894 Mahkam M, Allahverdipoor M: Controlled release of biomolecules from pH-sensitive network polymers prepared by radiation polymerization. J Drug Target. 2004 Apr;12(3):151-6.


Copolymers of 2-hydroxyethyl methacrylate (HEMA) and methacrylic acid (MAA) based hydrogels containing 5 and 10% of a cross-linking agent were studied as drug delivery systems.
3(0,0,0,3) Details
16054682 Lord MS, Stenzel MH, Simmons A, Milthorpe BK: The effect of charged groups on protein interactions with poly (HEMA) hydrogels. Biomaterials. 2006 Feb;27(4):567-75. Epub 2005 Jul 28.

3(0,0,0,3) Details
11354481 Jiang W, Irgum K: Synthesis and evaluation of polymer-based zwitterionic stationary phases for separation of ionic species. Anal Chem. 2001 May 1;73(9):1993-2003.


Three different zwitterionic functional stationary phases for chromatography were synthesized on the basis of 2-hydroxyethyl methacrylate (HEMA) polymeric particles.
3(0,0,0,3) Details
15171661 Chen JH, Chen QY, Sheng JR, Luo QZ: [Studies on design, synthesis and biodegradation of carrier for colon-site specific, drug delivery system]. Yao Xue Xue Bao. 2004 Mar;39(3):223-6.


METHODS: The azocopolymer P (HEMA-MMA-MAA) was synthesized using 2-hydroxyethylmethacrylate (HEMA), methyl methacrylate (MMA) and methacrylic acid (MAA) as comonmer, azobisisobutyronitrilel (AIBN) as initiator, cross-linked with divinylazobezene (DVAB).
3(0,0,0,3) Details
19238295 Ansell RJ, Wang D: Imprinted polymers for chiral resolution of (+/-)-ephedrine. Analyst. 2009 Mar;134(3):564-76. Epub 2008 Nov 28.


The monomers trifluoromethacrylic acid (TFMAA), 2-hydroxyethylmethacrylate (HEMA) and itaconic acid (IA) have been compared for the molecular imprinting of (-)-ephedrine.
3(0,0,0,3) Details
16302329 Mahkam M, Doostie L: The relation between swelling properties and cross-linking of hydrogels designed for colon-specific drug delivery. Drug Deliv. 2005 Nov-Dec;12(6):343-7.


Copolymers of 2-hydroxyethyl methacrylate (HEMA) and methacrylic acid (MAA)-based hydrogels containing 5% and 10% of a cross-linking agent were studied as drug delivery systems.
3(0,0,0,3) Details
15989482 Soroa VE, del Huerto Velazquez Espeche M, Giannone C, Caviglia H, Galatros G, Fernandez D, Mendez M, Naswetter GG, Nicolini JO: Effects of radiosynovectomy with p-32 colloid therapy in hemophilia and rheumatoid arthritis. Cancer Biother Radiopharm. 2005 Jun;20(3):344-8.


Clinical, blind evaluation (state of joint involvement, pain, motility, requirements of antihemophilic factors, corticoids, or analgesics) was registered in follow-up charts.
2(0,0,0,2) Details
18582574 Van Tomme SR, van Nostrum CF, Dijkstra M, De Smedt SC, Hennink WE: Effect of particle size and charge on the network properties of microsphere-based hydrogels. Eur J Pharm Biopharm. 2008 Oct;70(2):522-30. Epub 2008 Jun 6.


Copolymerization of hydroxyethyl methacrylate-derivatized dextran (dex-HEMA), emulsified in an aqueous poly (ethylene glycol) (PEG) solution, with methacrylic acid (MAA) or dimethylaminoethyl methacrylate (DMAEMA) resulted in negatively or positively charged microspheres, respectively, at physiological pH.
2(0,0,0,2) Details
18925620 Zhang S, Fu X, Wang H, Yang Y: Selective adsorption of D- and L-phenylalanine on molecularly-imprinted polymerized organogels formed using polymerizable gelator N-octadecyl maleamic acid. J Sep Sci. 2008 Dec;31(21):3782-7.


The polymerizable gelator N-octadecyl maleamic acid (ODMA) can self-assemble in selected polymerizable organic solvents, such as 2-hydroxyethyl methacrylate (HEMA) and methylacrylic acid (MAA) to form thermally stable polymerizable organogels.
2(0,0,0,2) Details
16303535 Tranoudis I, Efron N: Parameter stability of soft contact lenses made from different materials. Cont Lens Anterior Eye. 2004 Sep;27(3):115-31.


The following materials (and nominal water contents) were used: HEMA/VP 40%, HEMA/VP 55%, HEMA/VP 70%, VP/MMA 55%, VP/MMA 70%, HEMA 40%, HEMA/MAA 55% and HEMA/MAA 70% (HEMA: 2-hydroxy-ethyl methacrylate, VP: vinyl pyrrolidone, MMA: methyl methacrylate, MAA: methacrylic acid).
2(0,0,0,2) Details