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endrin

Identification (Source:EPA,EU)

ID	334
Name	endrin
CAS	72-20-8
IUPAC
Inchi	InChI=1S/C12H8Cl6O/c13-8-9(14)11(16)5-3-1-2(6-7(3)19-6)4(5)10(8,15)12(11,17)18/h2-7H,1H2/t2-,3+,4-,5+,6-,7+,10-,11+
CIPAC	28
EPA Code	041601
Formula	C12H8Cl6O
SMILES	Cl\C1=C(/Cl)C2(Cl)C3C4CC(C3C1(Cl)C2(Cl)Cl)C5OC45
Status	Not Approved

Classification

Mode of Action	Broad-spectrum, with contact and stomach action. Is a chloride channel-blocking agent.
Pesticide Type	Insecticide, Avicide, Rodenticide
Chemical Group	Organochlorine
Classification	cyclodiene insecticides Avicides

Properties (Source:PubChem)

Molecular Weight	380.91
Physical State	White crystals
AlogP	3.406
H-Bond Donor	0
H-Bond Acceptor	1
Surface Area	273.36
Polar Surface Area	12.53

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Aquatic invertebrates	Acute	48 hour	EC50	0.0042 mg l-1
Birds	Acute		LD50	5.6 mg kg-1
Earthworms	Acute	14 day	LD50	66 mg kg-1
Fish	Acute	96 hour	LC50	0.00073 mg l-1
Honeybees	Acute	48 hour	LD50	0.46 μg bee-1
Mammals	Acute oral		LD50	7.5 mg kg-1
	Bio-concentration factor		BCF	3970
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
cytochrome c	309(3,5,5,9)	Details
GABA receptor (protein family or complex)	156(1,3,4,11)	Details
catalase	105(1,1,4,10)	Details
adenylate cyclase	89(1,1,1,9)	Details
PPAR gamma	87(1,1,2,2)	Details
aryl hydrocarbon receptor	84(1,1,1,4)	Details
cytochrome P450 (protein family or complex)	83(1,1,1,3)	Details
CCAAT enhancer binding protein alpha	81(1,1,1,1)	Details
protein C	81(1,1,1,1)	Details
factor is	81(1,1,1,1)	Details
tumor necrosis factor alpha	81(1,1,1,1)	Details
ATPase	44(0,1,2,9)	Details
calmodulin	41(0,1,2,6)	Details
MC7	31(0,1,1,1)	Details
U82	31(0,1,1,1)	Details
muscles	23(0,0,3,8)	Details
brains	20(0,0,3,5)	Details
acid phosphatases	20(0,0,3,5)	Details

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